Soritec 25
Rx- Generic:
- Acitretin
- Company:
- ACI Limited
- Dosage form:
- Capsule
- Pack size:
- Box (10 Capsule)
৳ 85.26/unit
Pack: ৳ 852.60
Price comparison
- This brand
- ৳ 85.26
- Cheapest of this genericSoricap 25
- ৳ 85
The cheaper brand costs ৳ 0.26 less per unit
Compared against 2 brands
At a glance
Acitretin is a second-generation retinoid used for severe psoriasis and other keratinization disorders. It is a synthetic vitamin A analog that regulates abnormal skin cell growth.
Indications
Severe extensive psoriasis (resistant to other therapies); palmo-plantar pustular psoriasis; severe congenital ichthyosis; severe Darier's disease (keratosis follicularis).
Dosage
Adults and Elderly:
- Initial dose: 25-30 mg/day for 2-4 weeks.
- Maintenance dose: 25-50 mg/day for 6-8 weeks.
- Maximum dose: 75 mg/day.
- Darier's disease: Starting dose may be 10 mg/day, not exceeding 50 mg/day.
Children:
- Approximately 0.5 mg/kg/day (maximum 35 mg/day).
Side effects
Very common (>10%): Dry lips (cheilitis), dry skin, peeling, hair loss (alopecia).
Common (1-10%): Joint pain, muscle pain, itching, runny nose, nosebleeds, nail changes, headache, dry mouth.
Laboratory abnormalities: Increased triglycerides and cholesterol, decreased HDL, elevated LFTs.
Serious (rare): Liver damage (hepatitis), severe headache, nausea, vision problems, night blindness, depression, hyperglycemia.
Precautions & warnings
- Teratogenicity: Highly teratogenic. Absolutely contraindicated in pregnancy.
- Contraception: Women of childbearing potential must use 2 effective methods of contraception 1 month before, during, and for 3 years after treatment.
- Alcohol: Acitretin plus alcohol forms teratogenic etretinate. Alcohol is strictly prohibited during treatment and for 2 months after.
- Blood donation: Prohibited during and for 3 years after treatment.
- Liver and lipid monitoring: Regular LFTs and lipid profiles before and during treatment.
- Sun exposure: Skin becomes more sensitive; use sunscreen and protective clothing.