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At a glance

Drotaverine Hydrochloride is an antispasmodic medicine used in the treatment of menstrual pain, abdominal pain, pain due to kidney stones, biliary stones, and gastrointestinal colicky pain. It relieves smooth muscle spasms.

Indications
  • Gastric spasm
  • Intestinal spasm or pyloric spasm
  • Cholelithiasis (gallbladder stones)
  • Spastic constipation
  • Relief of tenesmus in dysentery
  • Dysmenorrhoea (menstrual pain)
  • Peripheral vascular disorders
  • Coronary insufficiency and angina pectoris
  • Abdominal pain
Pharmacology

Drotaverine HCl is a potent synthetic antispasmodic drug readily absorbed from the intestine. Like papaverine, it acts directly on smooth muscle fibers, exceeding the antispasmodic effect of standard preparations. It is characterized by rapid onset of action, advantageous in acute painful spastic conditions. In addition to spasmolytic and vasodilatory actions, Drotaverine HCl elicits selective blockage of cardiac beta-receptors.

Dosage

Adult Dose (Oral): 1-2 tablets, 3 times daily.

Adult Dose (Injection): 1-2 ampoules, intramuscularly or subcutaneously, 1-3 times daily. For acute stone colic: 1-2 ampoules by slow intravenous injection.

Child Dose (>6 years): 1/2-1 tablet, 1-2 times daily (40 mg).

Child Dose (1-6 years): 1/4-1/2 tablet, 1-2 times daily (20 mg).

Side effects

Common Side Effects:

  • Nausea
  • Vomiting
  • Dryness in mouth
  • Vertigo
Use in pregnancy

Information regarding the use of Drotaverine Hydrochloride during pregnancy is not available. Please consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Drotaverine Hydrochloride helps relieve pain due to smooth muscle spasms such as menstrual pain, kidney stone, and colicky pain.
  • Take as per dose and duration suggested by your doctor.
  • It may cause a drop in blood pressure. Monitor blood pressure regularly and inform doctor if you have history of low blood pressure.
  • Use caution while driving as it may cause dizziness.
  • Inform doctor if you have severe kidney, liver, or heart disease.
Overdose effects

Overdose may cause severe nausea, vomiting, vertigo and allergic reactions. Provide symptomatic treatment.

Storage conditions

Store in a cool, dry place. Keep out of reach of children.

Drotaverine Hydrochloride — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.