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At a glance

Pseudoephedrine Hydrochloride is a decongestant used for temporary relief of nasal congestion. It is an alpha- and beta-adrenergic receptor agonist that causes vasoconstriction via direct stimulation of alpha-adrenergic receptors of the respiratory mucosa, reducing nasal mucosal swelling and congestion.

Indications
  • Nasal congestion (temporary relief)
Pharmacology

Pseudoephedrine stimulates alpha-adrenergic receptors of the respiratory mucosa, causing vasoconstriction and reducing nasal mucosal swelling and congestion. It also stimulates beta-adrenergic receptors, causing bronchial relaxation and increased heart rate.

Dosage

Adult Dose (Oral):

  • Nasal congestion: 1 tablet (60 mg) every 4-6 hours; max 4 tablets/24 hours

Pediatric Dose (Oral):

  • 6-12 years: ½ tablet (30 mg) 3-4 times daily
  • 2-5 years: ¼ tablet (15 mg) 3-4 times daily
Side effects

Side Effects:

  • Anginal pain
  • Rebound congestion and rhinorrhea
  • Anxiety, restlessness, tremor, insomnia, confusion, irritability
  • Reduced appetite, nausea, vomiting
  • Reflex bradycardia, tachycardia, cardiac arrhythmias
  • Hypotension, dizziness, fainting, flushing
Use in pregnancy

Use in Pregnancy: Information regarding use during pregnancy is not available; consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Caution in hyperthyroidism, ischemic heart disease, arrhythmia, tachycardia, arteriosclerosis, hypertension, aneurysms, diabetes, closed-angle glaucoma, renal impairment, prostatic enlargement
  • Caution in pregnancy and lactation
  • Concentrated in breast milk
Overdose effects

Overdose: Hypertension, arrhythmias, seizures, cerebral hemorrhage; treatment: supportive care, blood pressure control.

Storage conditions

Store in a cool and dry place; keep out of reach of children.

Pseudoephedrine Hydrochloride — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.