৳ 25/unit
Pack: ৳ 250
৳ 25/unit
Pack: ৳ 250
At a glance
Suvorexant is an orexin receptor antagonist used for the treatment of insomnia, particularly difficulty with sleep onset and/or sleep maintenance. It works by blocking the action of wake-promoting neuropeptides orexin.
Indications
- Insomnia (difficulty with sleep onset and/or sleep maintenance)
Pharmacology
Suvorexant selectively antagonizes orexin receptors OX1R and OX2R. The orexin neuropeptide signaling system is a central promoter of wakefulness. Receptor blockade suppresses wake drive, making it easier to initiate and maintain sleep.
Dosage
Adult Dose (Oral):
- Recommended: 10 mg once nightly (30 minutes before bedtime)
- At least 7 hours remaining before planned awakening
- If tolerated but not effective, dose may be increased to 20 mg
- Use the lowest effective dose
Side effects
Common Side Effects:
- Daytime sleepiness
- Not thinking clearly
- Strange behavior, confusion, or upset
- Sleep-walking or complex behaviors
Use in pregnancy
Use in Pregnancy: No adequate controlled studies; use only if clearly needed; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Risk of daytime somnolence (especially at 20 mg dose); avoid driving
- Re-evaluate if insomnia persists after 7-10 days of treatment
- Depression or suicidal thinking may worsen
- Risk increases with alcohol and CNS depressants
Overdose effects
No specific overdose information; provide symptomatic and supportive treatment.
Storage conditions
Store in a cool and dry place, protected from light; keep out of reach of children.