Taven EZ 20/1020mg+10mg
Rx- Generic:
- Atorvastatin + Ezetimibe
- Company:
- Renata Limited
- Dosage form:
- Tablet
- Pack size:
- Box (20 Tablet)
৳ 22/unit
Pack: ৳ 440
At a glance
Atorvastatin + Ezetimibe — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Atorvastatin + Ezetimibe is a medicine used to treat high cholesterol. It is a combination of two medicines that reduces "bad" cholesterol (LDL) and triglycerides (fats) levels. Atorvastatin + Ezetimibe can be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. You can help this medicine work better by making a few changes to your lifestyle such as keeping active, stopping smoking, eating a healthy low-fat diet and exercise regularly. Nausea, stomach pain, constipation, and muscle pain are some common side effects of this medicine. These are usually mild but let your doctor know if they bother you or last more than a few days. Let your doctor know if you notice yellowing of skin or eyes, unusually dark urine or dark stools as it might be symptoms of liver damage. You may be asked for regular monitoring of blood sugar level, and liver function while taking this medicine. Before taking this medicine, let your doctor know if you have any kidney or liver problems or high blood pressure. Pregnant or breastfeeding women should also consult their doctor before taking it. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine. Atorvastatin + Ezetimibe is a combination of two medicines: Atorvastatin and ezetimibe. Atorvastatin is a lipid-lowering medicine which prevents your body from making "bad" cholesterol (LDL) while raising "good" cholesterol (HDL) levels. Ezetimibe is a cholesterol absorption inhibitor which prevents absorption of cholesterol from the intestines. Together, they provide better reduction of cholesterol in your body.
Indications
• High cholesterol
Mechanism of action
Atorvastatin competitively inhibits HMG-CoA reductase, the enzyme that catalyses the conversion of HMG-CoA to mevalonate which is an early rate-limiting step in cholesterol biosynthesis. Ezetimibe inhibits the absorption of cholesterol from the intestine, thus decreasing the delivery of intestinal cholesterol to the liver.
Dosage
Adult Dose: Oral Hypercholesterolaemia Adult: Per tablet contains atorvastatin 10 mg and ezetimibe 10 mg: Usual starting: 1 tablet once daily. Child Dose: Safety and efficacy not established
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Atorvastatin + Ezetimibe may be taken with or without food, but it is better to take it at a fixed time.
Side effects
Common: • Nausea • Constipation • Stomach pain • Headache • Muscle pain • Increased liver enzymes • Increased glucose level in blood
Precautions & warnings
[UNSAFE] Atorvastatin + Ezetimibe may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. You have been prescribed Tonact EZ Tablet for the treatment of high cholesterol. Take it in addition to regular exercise and low-fat diet to lower levels of fat in the blood. It can be taken with or without food. Notify your doctor if you experience muscle symptoms (pain or weakness), particularly if accompanied with fever. Notify your doctor if you experience stomach pain, loss of hunger, a sick feeling or dark urine.
Contraindications
Hypersensitivity; active liver disease or unexplained persistent elevated liver function tests. Pregnancy and lactation.
Drug interactions
Atorvastatin: Increases digoxin levels; increases anticoagulant effect of warfarin. Avoid the combination of HMG-CoA reductase inhibitors and fibrates. Ezetimibe: Cholestyramine decreases AUC of ezetimibe by approx 55%; ciclosporin may increase ezetimibe levels. Potentially Fatal: Antacids decrease atorvastatin levels; colestipol decreases atorvastatin plasma levels; propranolol decreases antihyperlipidaemic activity of atorvastatin.
Food interactions
[UNSAFE] It is unsafe to consume alcohol with Atorvastatin + Ezetimibe.
Use in pregnancy
[UNSAFE] Atorvastatin + Ezetimibe is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Use in lactation
[CONSULT YOUR DOCTOR] Atorvastatin + Ezetimibe is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Renal / hepatic impairment
[SAFE IF PRESCRIBED] Atorvastatin + Ezetimibe is safe to use in patients with kidney disease. No dose adjustment of Atorvastatin + Ezetimibe is recommended. [CAUTION] Atorvastatin + Ezetimibe should be used with caution in patients with liver disease. Dose adjustment of Atorvastatin + Ezetimibe may be needed. Please consult your doctor. Use of Atorvastatin + Ezetimibe is not recommended in patients with moderate to severe liver disease.
Common questions
Please tell me the difference of tonact tg or tonact 20. The attributes being which is lighter , better to intake. Tonact tg contains two drugs atorvastatin and fenofibrate which helps to reduce ldl increase hdl cholesterol and to reduce triglyceride level whereas tonact 20 only contains atorvastatin which helps to reduce ldl and increase hdl cholesterol only. High BP since 10 years. Under control by high dose allopathic medicines. Lipid Profile normal by using Tonact 75mg. Case has to be seen in person before starting the treatment High triglycerides past 5 years last test 545 taking tonact tg 20 and having thyroid prblm also taking thyronorm 50 Restrict carbs in diet stop taking sugars After having tuberculosis diagnosed she has been recommended to have R cinex EZ 2 tablets daily for 2 months then after 1tablet Risorine for 1 month and now doctor has recommended onceagain to have R cinex EZ 2tables on alternate days what to do. TB treatment is in 2 phases1. Intensive phase where tabs RHZE are given as in your case and in the second phase called continuation phase one one the medicines is stopped nad others continued.Please discuss with your doctor or see another doctor nearby for opinion since , the treatment may have to be modified, read about TB at http://www.arohealth.com/pulmonary-tuberculosis/ Triglocite is 334 mg I am taking tonact asp75 but getting breathless shall continue or not Consult cardiologist at ur place get angio done Sir my lipid profile total 137. Triclyc 100. Hdl 56. Ldl 61 Vldl 20 i f i want to take tablet. Already i was taken Tonact tg 10mg. Take tablet or noneed please reply sir. No need of medicines restrict carbs n regularly exercise Suffered stroke 2 years back. Currently taking Preva As 150, Tonact 20, Cobal F daliy. Still my left hand pains. tab maxgalin 75 mg hs