৳ 8.50/unit
Pack: ৳ 85
৳ 8.50/unit
Pack: ৳ 85
At a glance
Non-steroidal anti-inflammatory drug (NSAID) used for pain and inflammation in musculoskeletal disorders and post-operative pain.
Indications
Indicated for pain and inflammation in musculoskeletal and joint disorders such as rheumatoid arthritis, osteoarthritis, low back pain, and post-operative pain.
Pharmacology
Acemetacin acts as a prodrug converted to indomethacin in the body. It inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis responsible for pain and inflammation.
Dosage
Recommended starting dose is 120 mg/day in divided doses, increasing up to 180 mg/day in divided doses depending on clinical response.
Side effects
Common: Anorexia, nausea, vomiting, diarrhea, constipation, peptic ulceration, headache, dizziness, vertigo. Rare: Confusion, depression, edema, chest pain, elevated blood urea.
Use in pregnancy
Pregnancy Category C (Category D in 3rd trimester). Not recommended during pregnancy as safety is not established.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Use with caution in elderly patients, those with a history of GI disorders, IBD, kidney disease, liver disease, or heart failure.
Overdose effects
Overdose may cause severe headache, nausea, abdominal pain, or GI bleeding. Symptomatic and supportive treatment is required.
Storage conditions
Store below 25°C in a cool, dry place away from light. Keep out of reach of children.