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At a glance

Teriparatide is a parathyroid hormone analog (PTH 1-34) used for the treatment of osteoporosis in postmenopausal women and men at high risk for fracture. It stimulates new bone formation.

Indications
  • Osteoporosis in postmenopausal women at high risk for fracture
  • Bone mass increase in men with primary or hypogonadal osteoporosis at high risk for fracture
  • Glucocorticoid-induced osteoporosis in men and women at high risk for fracture
Pharmacology

Teriparatide activates PTH receptors, increasing osteoblastic activity and stimulating new bone formation. Once-daily administration favors bone formation over resorption, increasing bone mineral density and strength.

Dosage

Adult Dose (SC):

  • Recommended: 20 mcg subcutaneously once daily
  • Treatment duration: Maximum 2 years in a lifetime
Side effects

Common Side Effects:

  • Arthralgia (joint pain)
  • Pain
  • Nausea

Other:

  • Hypercalcemia (transient)
  • Dizziness (orthostatic hypotension)
  • Injection site reactions
Use in pregnancy

Use in Pregnancy: Insufficient data; consider discontinuing teriparatide if pregnancy is recognized; consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Do not use in Paget's disease, pediatric/young adults with open epiphyses, or prior skeletal radiation therapy
  • Do not use in bone metastases, history of skeletal malignancies, metabolic bone diseases other than osteoporosis, or hypercalcemic disorders
  • Caution in active or recent urolithiasis
  • Do not use for more than 2 years in a lifetime
Overdose effects

Overdose may cause hypercalcemia, nausea, dizziness; temporarily discontinue, increase hydration; provide symptomatic treatment.

Storage conditions

Store at 2-8°C in a refrigerator; do not freeze; do not use if frozen; keep out of reach of children.

Teriparatide — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.