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At a glance

Tolfenamic Acid is a pain relieving medicine used for acute migraine attacks and mild to moderate pain. It is an NSAID that works by blocking chemical messengers that cause fever, pain, and inflammation.

Indications
  • Acute migraine attacks
  • Mild to moderate pain
  • Post-operative pain and fever
Pharmacology

Tolfenamic acid inhibits cyclooxygenase enzyme, thus inhibiting synthesis of inflammatory mediators such as thromboxane B2 and prostaglandin E2. It also has direct antagonistic action on prostaglandin receptors.

Dosage

Adult Dose (Oral):

  • Acute migraine: 200 mg at first symptoms; may repeat after 1-2 hours if necessary
  • Mild to moderate pain: 100-200 mg three times daily
  • Severe renal/hepatic impairment: Avoid
Side effects

Common Side Effects:

  • Vomiting
  • Nausea
  • Indigestion
  • Diarrhea
  • Heartburn
  • Loss of appetite
Use in pregnancy

Use in Pregnancy: May be unsafe; limited human studies, animal studies show harmful effects; consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • May decrease alertness, affect vision, or cause dizziness; do not drive
  • Long-term use may cause stomach bleeding and kidney problems
  • May increase risk of blood clots, heart attack, or stroke
  • Consult doctor if pregnant, planning to conceive, or breastfeeding
Overdose effects

Symptoms: Headache, nausea, vomiting, GI bleeding, drowsiness, dizziness, convulsions.

Treatment: Symptomatic and supportive.

Storage conditions

Store in a cool and dry place, away from light; keep out of reach of children.

Tolfenamic Acid — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.