৳ 10/unit
Pack: ৳ 100
৳ 10/unit
Pack: ৳ 100
At a glance
Benzonatate is a non-narcotic antitussive used for the symptomatic treatment of cough. It acts peripherally by anesthetizing the stretch receptors in the respiratory passages and lungs, reducing the cough reflex at its source.
Indications
- Cough
Pharmacology
Benzonatate acts peripherally by anesthetizing the stretch receptors located in the respiratory passages, lungs, and pleura by dampening their activity and thereby reducing the cough reflex at its source. It begins to act within 15 to 20 minutes and its effect lasts for 3 to 8 hours.
Benzonatate is chemically related to anesthetic agents of the para-amino-benzoic acid class (e.g., procaine, tetracaine) and has been associated with adverse CNS effects.
Dosage
Adults and Children (10 years and older): 100 mg, 150 mg, or 200 mg capsule three times daily (every 8 hours). If necessary to control cough, up to 600 mg daily in three divided doses may be given.
Children (under 10 years): Safety and efficacy have not been established.
Side effects
- Hypersensitivity reactions (bronchospasm, laryngospasm, cardiovascular collapse)
- Sedation
- Headache
- Dizziness
- Constipation
- Nausea
- Pruritus
- Skin eruptions
- Nasal congestion
- Burning sensation in eyes
- Chest numbness
- Chilly sensation
- Confusion
- Hallucinations
Use in pregnancy
[CONSULT YOUR DOCTOR] Insufficient data on safety during pregnancy (Category C). Animal reproduction studies have not been conducted. Use only if clearly needed.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Keep out of reach of children - accidental ingestion in children under 10 years has resulted in death
- Chewing or sucking capsules may cause local anesthesia leading to serious reactions
- Deliberate or accidental overdose has resulted in death, particularly in children
- Isolated cases of bizarre behavior (mental confusion and visual hallucinations) have been reported
- Benzonatate is chemically related to para-amino-benzoic acid class anesthetics
Overdose effects
Symptoms: Signs of overdose appear within 15-20 minutes. Chewing or dissolving capsules may cause rapid oropharyngeal anesthesia, leading to choking and airway compromise.
Treatment: Seek emergency medical attention immediately. Evacuate gastric contents and administer copious amounts of activated charcoal slurry.
Storage conditions
Store below 25°C in a cool and dry place, protected from light. Keep out of reach of children.