৳ 195/unit
Pack: ৳ 5,850
৳ 195/unit
Pack: ৳ 5,850
At a glance
Ulipristal Acetate is a selective progesterone receptor modulator used to treat uterine fibroids. It reduces symptoms like vaginal bleeding, prolonged periods, and lower back pain. It is also used for emergency contraception.
Indications
- Uterine fibroids
- Emergency contraception
Pharmacology
Ulipristal Acetate is a selective progesterone receptor modulator with antagonistic and partial agonistic effects. When taken immediately before ovulation, it postpones follicular rupture. The primary mechanism of action for emergency contraception is inhibition or delay of ovulation; however, alterations to the endometrium that may affect implantation may also occur.
Dosage
Adult Dose (Oral):
- Emergency contraception: One tablet as soon as possible within 120 hours (5 days) after unprotected intercourse or contraceptive failure
- Uterine fibroids: 5 mg once daily for up to 3 months; this 3-month course can be repeated once; re-treatment should start during the second menstruation following the first course; treatment should always be started during the first week of menstruation
- If a dose is missed, take as soon as possible; if missed by >12 hours, skip the missed dose and resume the usual dosing schedule
Side effects
Common Side Effects:
- Absence of menstrual periods
- Headache
- Endometrial hyperplasia
Use in pregnancy
Use in Pregnancy: Highly unsafe; studies show significant harmful effects to the developing baby; consult your doctor.
Pregnancy Category: X — always consult a doctor before taking during pregnancy.
Precautions & warnings
- May affect ability to drive
- Dizziness, drowsiness, blurred vision, or loss of concentration may occur; do not drive if these symptoms occur
- Menstrual bleeding considerably reduces or stops within the first 10 days of treatment; notify doctor if heavy bleeding continues
- Periods usually start again within four weeks of stopping
- May make hormonal contraceptives less effective; use reliable barrier contraceptive
- Routine blood tests may be needed to assess liver function
- Inform doctor if yellowing of skin/eye, dark urine, or stomach pain occurs
Overdose effects
Symptoms: Absence of menstrual periods, headache, endometrial hyperplasia.
Treatment: Supportive care.
Storage conditions
Store in a cool and dry place; keep out of reach of children.