Unitin 10

Isotretinoin belongs to a group of medicines called retinoids, which are closely related to vitamin A derivative. It is used to treat severe acne that has not responded to other treatments. Isotretinoin should be used in the dose and duration as advised by your doctor. It should be taken with food, preferably at the same day, each day to avoid a missed dose. It may take several weeks for your symptoms to improve but keep using it regularly to get the most benefit. If you notice no improvement after a few weeks, see your doctor again. Using more medicine or applying it more often than prescribed will not make it work any faster and may increase side effects. The most common side effects include dry skin, rash and increased liver enzymes. They are not usually serious and often disappear after getting used to the cream but if they bother you or do not go away, tell your doctor. You may need to apply smaller amounts or use it less often. Serious side effects are rare. Isotretinoin may make you more sensitive to sunlight so you should limit exposure to the sun if possible. Drink plenty of water and use moisturizer as it may lead to dryness of the mouth, lips and eyes. It may make your skin more fragile. It is advised, not to have any waxing (hair removal), or laser treatments during treatment. This medicine may lead to birth defects, do consult your doctor if you are pregnant or planning to get pregnant. Isotretinoin is a derivative of vitamin A. It acts on glands (sebaceous) to reduce the production of a natural substance (sebum) that causes acne. Also, the controlled sebum production kills acne-causing bacteria. It also works as an anti-inflammatory to decrease inflammation (redness and swelling).

• Acne

Isotretinoin is a synthetic retinoid which reduces sebaceous gland size and sebum production. It also regulates cell proliferation and differentiation.

Adult Dose: Oral Severe, Recalcitrant Nodular Acne Severe nodular acne unresponsive to conventional therapy, including systemic antibiotics Adult: 0.5-1 mg/kg/day PO divided BID for 15-20 weeks Dose up to 2 mg/kg/day (as tolerated) if disease is very severe with scarring or is primarily manifested on the trunk Hepatic impairment: Contraindicated. Child Dose: Severe, Recalcitrant Nodular Acne Severe nodular acne unresponsive to conventional therapy, including systemic antibiotics 12 years: 0.5-1 mg/kg/day PO divided BID for 15-20 weeks Dose up to 2 mg/kg/day (as tolerated) if disease is very severe with scarring or is primarily manifested on the trunk Renal Dose: Renal impairment: Severe: Reduce initial dose (e.g. 10 mg daily), then gradually increase to 1 mg/kg as necessary.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isotretinoin is to be taken with food.

If you miss a dose of Isotretinoin, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Dry skin

[UNSAFE] Isotretinoin may cause side effects which could affect your ability to drive. Your night vision may get worse during your treatment. This can happen suddenly. Drowsiness and dizziness have been reported very rarely. This may affect your driving ability. Take it with food. Avoid exposure to sunlight while using Isotretinoin. Use protective measures such as sun-cream or protective clothing. Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile. Avoid taking tetracycline as it may reduce the Isotretinoin activity. Do not take Isotretinoin if you are pregnant, planning pregnancy or breastfeeding. It may cause dryness of mouth, lips, and eyes. Drink plenty of water, use moisturiser and avoid wearing contact lenses. Inform your doctor if it bothers you.

Pregnancy, lactation.

Additive toxicity with vitamin A or its derivatives. Decreased efficacy of microdosed progesterone (use 2 forms of contraception). May increase risk of bone loss with phenytoin. May increase risk of osteoporosis with systemic corticosteroids. Reduces plasma levels of carbamazepine. Potentially Fatal: Increased risk of pseudotumor cerebri with tetracyclines.

[CAUTION] Caution is advised when consuming alcohol with Isotretinoin. Please consult your doctor.

[UNSAFE] Isotretinoin is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

[CONSULT YOUR DOCTOR] Isotretinoin is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[SAFE IF PRESCRIBED] Isotretinoin is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Isotretinoin may not be needed in these patients. Please consult your doctor. If you experience excessive tiredness, puffy eyes and difficulty in urination while taking this medicine, inform your doctor and stop the therapy. [UNSAFE] Isotretinoin is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

i take isotroin 20 mg tabs for acne by docs advice i got lowerbackache after take it is it common or something else?can i keep moving on or not? Hw long r u taking isotroin This problem is not commonly seen with isotretinoin. . Still i'LL suggest u to visit the doctor u'r consulting. an xray and if reqd MRI may be needed bt first of all visit the doctor so that he can revaluate u Can i take tab isotroin 20mg with tab juliana (hormonal pill ) depends completely on the disease you have other comorbidities etc. which can't be assessed online this way for that you must visit the chamber if you're under treatment of a dermatologist then visit him so as to rule out any contraindications How should i take involym capsule in a day isotroin 10 mg pls preferred a time to take In empty stomach or after food Please Ask the doctor who had prescribed Having pimples on face since 3 years During mc it cums more I m taking isotroin 20mg from 20days Then also pimples is cuming on face and neck you need to understand that getting a few acne lesions on face on n off is okay but keeping your age in mind, if you are getting a large number of acne lesions, then you need a hormonal profile. As for now apply Clindac A gel twice daily and Cetaphil cleansing lotion for oily skin. i have some acne only on my face and i am using isotroin 10 mg for that but i am also facing another issue from last 4-5 months. my skin gets swelled like patches at anytime and anywhere along with severe itching. kindly assist me Isotroin is a very strong medicine . It is very effective but can have side effects on the liver and cholesterol. Correct dose and duration is important . Consult directly.Kindly send pictures of affected area for better diagnosis and treatment. Hi Doctor, I am PCOD patient and suffering backacne also. whenever i use medicine for Acne such as isotroin 20 it impact adversely on my periods cycle. Please suggest me some cure so that i can treat PCOD and backacne as well side by side. Thanks PATIENT Dear sir as your case is a chronic case it requires long case taking, examination and regular follow up, therefore, please visit a homeopath so that he can examine you and guide you accordingly. Can I take Acnestar from mankind instead of sortet from sunpharma ? Can this be done for all other medicines if I am able to find a substitute ? And why is there such price difference if the drug is same Always consult directly before starting IsotretinoinIsotroin is a very strong medicine . It is very effective but can have side effects on the liver and cholesterol. Correct dose and duration is important . Consult directly. I have been continuously taking medicines for acne but its not going away, Isotroin was medicine which was given but i have stopped taking that before 1 year because it was not working, what should I do now? Face clin gel for application twice daily over pimplesPlease send details of other medicinesTests :- complete blood picture , fasting lipid profile , liver function test