৳ 10/unit
Pack: ৳ 60
৳ 10/unit
Pack: ৳ 60
At a glance
Tamsulosin Hydrochloride is an alpha-1 adrenergic antagonist used for the treatment of functional symptoms of Benign Prostatic Hyperplasia (BPH). It relaxes muscles in the prostate and bladder neck to improve urine flow.
Indications
- Functional symptoms of Benign Prostatic Hyperplasia (BPH)
Pharmacology
Tamsulosin blocks alpha-1 adrenoceptors in the prostate, prostatic capsule, prostatic urethra, and bladder neck, relaxing smooth muscle. It is selective for alpha-1A receptors in the prostate, minimizing effects on blood pressure. This improves urine flow and reduces BPH symptoms.
Dosage
Adult Dose (Oral):
- Start: 0.4 mg (1 capsule) once daily (after the evening meal)
- If needed, increase to 0.8 mg (2 capsules) once daily after 2-4 weeks
- After interruption, restart at 0.4 mg/day
Side effects
Common Side Effects:
- Dizziness
- Abnormal ejaculation (retrograde ejaculation)
- Nasal congestion
- Headache, asthenia
- Postural hypotension, palpitations
Use in pregnancy
Use in Pregnancy: Generally safe; animal studies show low or no adverse effects; limited human data; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Do not use in history of orthostatic hypotension
- Do not use in severe hepatic insufficiency
- IFIS (Intraoperative Floppy Iris Syndrome) – inform ophthalmologist before cataract surgery
- May affect driving ability (dizziness)
Overdose effects
No acute overdose data; overdose may cause acute hypotension; lie patient down; use volume expanders and vasopressors if needed; dialysis is not effective (protein-bound).
Storage conditions
Store below 30°C in a cool and dry place, protected from light; keep out of reach of children.