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At a glance

Valdecoxib is a pain relieving medicine. It alleviates pain, redness, and swelling in various conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.

Indications
  • Pain relief
  • Rheumatoid arthritis
  • Osteoarthritis
  • Ankylosing spondylitis
  • Dysmenorrhoea
Pharmacology

Valdecoxib acts by selectively inhibiting prostaglandin synthesis primarily by blocking cyclooxygenase (COX-2) enzyme.

Dosage

Adult Dose (Oral):

  • Osteoarthritis, Rheumatoid arthritis: 10 mg once daily
  • Dysmenorrhoea: 20 mg twice daily
  • Hepatic impairment (Child-Pugh 7-9): Initiate with caution; Child-Pugh >10: Avoid
  • Renal impairment (CrCl <30): Initiate with caution
Side effects

Common Side Effects:

  • Diarrhea
  • Flatulence
  • Flu-like symptoms
  • Peripheral edema
  • Stomach pain
  • Nausea
  • Change in blood pressure
  • Backache
Use in pregnancy

Use in Pregnancy: May be unsafe; animal studies show harmful effects; consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • May affect ability to drive
  • May cause dizziness and fatigue; do not drive
  • Avoid alcohol; may cause excessive drowsiness
  • Monitor blood pressure regularly, particularly in the first two weeks
  • Inform doctor if history of stomach ulcers, heart diseases, high blood pressure, liver or kidney disease
  • Regular blood tests may be needed during long-term treatment
  • Do not use if pregnant, planning to conceive, or breastfeeding
Overdose effects

Symptoms: Dizziness, fatigue, stomach pain.

Treatment: Supportive care.

Storage conditions

Store in a cool and dry place; keep out of reach of children.

Valdecoxib — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.