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Company•Popular Pharmaceuticals Ltd.

Vasculex

10mg/mlRx
Generic: Phenylephrine Hydrochloride

৳ 40/unit

Pack: ৳ 40

Injection5ml Ampoule
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At a glance

Phenylephrine Hydrochloride injection is used for the treatment of clinically important hypotension resulting primarily from vasodilation in the setting of anesthesia. It is an α-1 adrenergic receptor agonist that increases systolic and diastolic blood pressures.

Indications
  • Clinically important hypotension resulting from vasodilation during anesthesia
Pharmacology

Phenylephrine is an α-1 adrenergic receptor agonist that increases systolic and diastolic blood pressures, mean arterial pressure, and total peripheral vascular resistance following IV administration. Increased blood pressure leads to increased vagal activity, resulting in reflex bradycardia.

Dosage

Adult Dose (Intravenous):

  • Hypotension during anesthesia: Recommended initial dose 40-100 mcg IV bolus
  • Additional boluses may be given every 1-2 minutes as needed; not to exceed 200 mcg in a single administration
Side effects

Side Effects:

  • Reflex bradycardia
  • Ischemia
  • Hypertension
  • Vomiting
  • Nausea
  • Neck pain
  • Tremors
Use in pregnancy

Use in Pregnancy: Data from randomized controlled trials and meta-analyses during cesarean section; no data on use during first or second trimester.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Exacerbation of Angina, Heart Failure, or Pulmonary Arterial Hypertension: May precipitate angina in patients with severe arteriosclerosis or history of angina; exacerbate underlying heart failure; increase pulmonary arterial pressure
  • Bradycardia: Can cause severe bradycardia and decreased cardiac output
  • Renal Toxicity: May increase need for renal replacement therapy in septic shock patients; monitor renal function
Overdose effects

Overdose: Rapid rise in blood pressure; symptoms include headache, vomiting, hypertension, reflex bradycardia, fullness in the head, tingling of extremities, and cardiac arrhythmias.

Storage conditions

Store below 30°C in a dry place, protected from light; keep out of reach of children.

Phenylephrine Hydrochloride — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.