osudhkosh
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At a glance

Broad-spectrum benzimidazole anthelmintic for single and mixed intestinal and tissue worm infestations.

Indications

Indicated in infestations of Hookworm, Roundworm, Threadworm, Whipworm, Strongyloides, Tapeworm, Opisthorchis, Giardiasis, and Hydatid disease.

Pharmacology

Albendazole blocks glucose uptake in susceptible helminths, depleting their energy levels. It inhibits parasite tubulin polymerization. It undergoes rapid first-pass metabolism to the active metabolite albendazole sulphoxide (half-life ~8.5 hours).

Dosage

Adults & Children >2 years: 400 mg as a single dose for common worms. For strongyloidiasis or taeniasis: 400 mg daily for 3 consecutive days. Children 1-2 years: 200 mg single dose. Hydatid disease (>60 kg): 400 mg twice daily for 28 days.

Side effects

Gastrointestinal discomfort, headache, dizziness, elevated liver enzymes, reversible alopecia, and rarely blood disorders (leukopenia, pancytopenia).

Use in pregnancy

FDA Pregnancy Category C. Contraindicated in pregnancy and women planning pregnancy.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings

Perform blood counts and liver function tests before and during treatment cycles in Hydatid disease. Exclude pregnancy prior to initiating therapy.

Overdose effects

Symptomatic treatment and supportive care should be initiated upon accidental overdose.

Storage conditions

Store in a dry place below 30°C, protected from light and heat. Keep out of reach of children.

Albendazole — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.