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Betahistine Dihydrochloride is used to prevent and treat a disorder of the inner ear known as Ménière’s disease. The symptoms include dizziness (vertigo), ringing in the ears (tinnitus) and loss of hearing, probably caused by fluid in the ear. This medicine helps relieve the symptoms by reducing the amount of fluid. Betahistine Dihydrochloride should be swallowed whole with water and taken at the same time(s) each day to get the most benefit. Your doctor will decide what is the correct dose to relieve your symptoms and how often you need to take it. You may need to take this medicine for several months and you should take it for as long as you prescribed by your doctor, even if you start feeling better. The most common side effects include headache, feeling sick and indigestion (dyspepsia). You may also get stomach pain and bloating. Taking the medicine with food can help reduce stomach problems. Before taking this medicine, you should talk to your doctor if you have a stomach ulcer, asthma or high or low blood pressure. You must also tell him/her what other medicines you are taking, to make sure you are safe. Also speak to your doctor if you are pregnant, trying to become pregnant or breastfeeding. Betahistine Dihydrochloride is a histamine analog. It works by improving the blood flow in the inner ear which reduces the pressure of excess fluid there. Excess fluid can send signals to the brain causing nausea, dizziness or spinning sensations (symptoms of Ménière's disease). Betahistine Dihydrochloride additionally dampens down the nerve signals sent from the inner ear to the brain relieving the symptoms of Ménière's disease.

• Meniere's disease

Betahistine improves the microcirculation in the labyrinth which reduces endolymphatic pressure.

Adult Dose: Adult: Initially, 8-16 mg tid. Maintenance: 24-48 mg daily.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Betahistine Dihydrochloride may be taken with or without food, but it is better to take it at a fixed time.

If you miss a dose of Betahistine Dihydrochloride, skip it and continue with your normal schedule. Do not double the dose.

Common: • Headache • Nausea

[SAFE] Betahistine Dihydrochloride does not usually affect your ability to drive. You have been prescribed Betahistine Dihydrochloride to relieve vertigo (dizziness), hearing problems and tinnitus (noise in the ear) associated with Ménière's disease. It can only decrease the number and severity of attacks but may not completely stop them. Taking it with food can help reduce stomach problems. Take it at the same time each day to maintain a steady amount of the medicine in your body. Inform your doctor if you have a history of stomach ulcer, asthma, or low blood pressure. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. Do not stop taking the medicine suddenly without talking to your doctor first.

Phaeochromocytoma. Porphyria.

May antagonise antihistamines. May decrease bronchodilator effects of beta-2 agonists.

[SAFE] Consuming alcohol with Betahistine Dihydrochloride does not cause any harmful side effects.

[CONSULT YOUR DOCTOR] Information regarding the use of Betahistine Dihydrochloride during pregnancy is not available. Please consult your doctor.

[CONSULT YOUR DOCTOR] Information regarding the use of Betahistine Dihydrochloride during breastfeeding is not available. Please consult your doctor.

[SAFE IF PRESCRIBED] Betahistine Dihydrochloride is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Betahistine Dihydrochloride may not be needed in these patients. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Betahistine Dihydrochloride in patients with liver disease. Please consult your doctor.

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