Vildium 25/62.5 Renacap
25mcg+62.5mcgRx৳ 80/unit
Pack: ৳ 2,400
৳ 80/unit
Pack: ৳ 2,400
At a glance
Vilanterol Trifenatate + Umeclidinium Bromide is indicated as a maintenance bronchodilator treatment to relieve symptoms in adult patients with chronic obstructive pulmonary disease (COPD).
Indications
- Chronic obstructive pulmonary disease (COPD)
Pharmacology
This dry powder inhaler capsule contains a combination of umeclidinium (an anticholinergic) and vilanterol (a LABA). Vilanterol stimulates β2-adrenoceptors, increasing cyclic AMP, which relaxes bronchial smooth muscle. Umeclidinium inhibits M3 receptor, leading to bronchodilation.
Dosage
Adult Dose (Inhalation):
- COPD maintenance: 25/62.5 mcg inhalation capsule once daily
- Use at the same time every day, not more than once every 24 hours
Side effects
Common Side Effects:
- Pharyngitis
- Sinusitis
- Lower respiratory tract infection
- Constipation
- Diarrhea
- Hand pain
- Muscle spasms
- Neck pain
- Chest pain
Use in pregnancy
Use in Pregnancy: Insufficient data on use in pregnant women.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Not indicated for relief of acute bronchospasm
- LABA monotherapy increases risk of serious asthma-related events
- Do not initiate in acutely deteriorating COPD
- Do not use in combination with additional LABA-containing therapy
- If paradoxical bronchospasm occurs, discontinue and institute alternative therapy
- Use with caution in patients with cardiovascular disorders
- Worsening of narrow-angle glaucoma may occur; caution advised
- Worsening of urinary retention may occur; caution in prostatic hyperplasia or bladder-neck obstruction
- Monitor for hypokalemia and hyperglycemia
Overdose effects
Symptoms: Very limited clinical experience.
Treatment: Supportive care.
Storage conditions
Avoid storage in direct sunlight or heat. Store in a cool & dry place. Keep away from eyes. Keep out of reach of children.