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At a glance

Voglibose is an alpha-glucosidase inhibitor used primarily in the management of non-insulin-dependent diabetes mellitus (NIDDM) to control postprandial blood glucose levels.

Indications

: Indicated for NIDDM (monotherapy or combined with other oral hypoglycaemic agents/insulin), prevention of type 2 diabetes in impaired glucose tolerance, glycogen storage disease type Ib, and non-diabetic hyperinsulinemia.

Pharmacology

Acts as a competitive inhibitor of alpha-glucosidase enzymes in the brush border of the small intestine, delaying the digestion and absorption of complex carbohydrates to reduce postprandial hyperglycemia.

Dosage

Adult Dose: Oral Diabetes mellitus Adult: 200-300 mcg tid. Elderly: Initiate at lower doses.

Side effects

Common: • Skin rash • Flatulence • Abdominal pain • Diarrhea

Use in pregnancy

[SAFE IF PRESCRIBED] Voglibose is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Precautions & warnings

[SAFE] Voglibose does not usually affect your ability to drive. Voglibose is used together with other diabetes medicines to control blood sugar and avoid long-term complications. You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Voglibose. Voglibose lowers your post-meal blood sugar levels. Therefore, it should be taken before meals. Side effects such as stomach pain, gas, and diarrhea may occur during the first few weeks of treatment but should get better with time.

Overdose effects

Does not cause hypoglycemia. May result in a transient increase in flatulence, diarrhea, and abdominal discomfort. Manage with supportive care.

Storage conditions

Store in a cool (below 30°C) and dry place, away from light. Keep out of children's reach.

Voglibose — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.