৳ 28/unit
Pack: ৳ 168
৳ 28/unit
Pack: ৳ 168
At a glance
Fluvoxamine Maleate is an SSRI antidepressant used for the treatment of depression and obsessive-compulsive disorder.
Indications
- Obsessive-Compulsive Disorder
- Depressive illness
- Panic Disorder
- Eating Disorder
- Chronic Tension Headache
Pharmacology
Fluvoxamine blocks the reuptake of serotonin at the serotonin reuptake pump of the neuronal membrane, enhancing the actions of serotonin on 5HT1A autoreceptors. Studies have also demonstrated that fluvoxamine has virtually no affinity for α1- or α2-adrenergic, β-adrenergic, muscarinic, dopamine D2, histamine H1, GABA-benzodiazepine, opiate, 5-HT1, or 5-HT2 receptors, despite having an affinity for binding to σ1 receptors.
Dosage
Obsessive-Compulsive Disorder (Adult):
- Initially: 50 mg in the evening for 3-4 days.
- If necessary, increase to 300 mg daily (over 150 mg in divided doses).
Obsessive-Compulsive Disorder (Child, 8+ years):
- Initially: 25 mg daily.
- If necessary, increase by 25 mg every 3-4 days to max 200 mg daily in divided doses.
Depression (Adult):
- Initially: 50-100 mg daily in the evening.
- If necessary, increase to 300 mg daily (over 150 mg in divided doses).
- Usual maintenance dose: 100 mg daily.
Children (Depression): Not recommended.
* Use as directed by the registered physician
Side effects
Common Side Effects:
- Nausea
- Vomiting
- Dryness in mouth
- Drowsiness
- Insomnia
- Headache
- Increased sweating
- Tremor
- Sexual dysfunction
Use in pregnancy
Use in Pregnancy: May be unsafe during pregnancy. Animal studies have shown harmful effects. Your doctor will weigh the benefits and risks.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Precautions:
- Use with caution in patients with a history of mania, seizures, suicidal tendency, cardiac disease, diabetes mellitus, angle-closure glaucoma, history of bleeding disorders.
- May impair performance of skilled tasks (driving).
- Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
- Do not stop taking the medication suddenly without talking to your doctor.
Overdose effects
Overdose:
- Symptoms: Gastrointestinal complaints (nausea, vomiting, diarrhea), somnolence, dizziness, tachycardia, bradycardia, hypotension, convulsions, coma.
- Treatment: No specific antidote. Empty stomach and give symptomatic treatment. Medicinal charcoal may be used.
Storage conditions
Storage: Store below 25°C, in a cool and dry place, away from light. Keep out of reach of children.