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At a glance
Alfuzosin Hydrochloride is an alpha-1 adrenergic receptor blocker used to relieve the symptoms of benign prostatic hyperplasia (BPH) or prostate enlargement . It relaxes the muscles in the prostate, bladder neck, and urethra to improve urine flow . It does not shrink the prostate but helps with symptoms like difficulty urinating, frequent urination at night, and incomplete bladder emptying . In Bangladesh, it is available as Alfasin XR (Incepta Pharmaceuticals), Flotral, Uriten (Square Pharmaceuticals), Zatral (Eskayef), etc., in 10 mg extended-release tablets .
Indications
• Benign Prostatic Hyperplasia (BPH): Treatment of the signs and symptoms of BPH. • Lower Urinary Tract Symptoms (LUTS): Treatment of BPH-associated urinary frequency, nocturia, incomplete bladder emptying, and urinary hesitancy. • Acute Urinary Retention (AUR): Adjuvant treatment with catheterization, particularly in patients aged 65 years and older.
Dosage
Benign Prostatic Hyperplasia (BPH): • Recommended dose: 10 mg tablet once daily, taken immediately after a meal. Acute Urinary Retention (AUR): • In patients aged 65 years and older: 10 mg once daily, taken after a meal, starting from the first day of catheterization. • Duration of treatment: 3–4 days (2–3 days while the catheter is in place and 1 day after catheter removal).
Side effects
Common: • Dizziness • Headache • Tiredness
Precautions & warnings
[UNSAFE] Alfuzosin may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Flotral 10 Tablet PR helps in relieving the symptoms of enlarged prostate. It does not decrease the size of the prostate. Flotral 10 Tablet PR must be taken with food. You will feel better within hours or days of starting the treatment. Full effect is usually seen within 2 weeks. Flotral 10 Tablet PR may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you. If you are scheduled to undergo an eye surgery due to cataract or glaucoma, inform your eye doctor about the usage of Flotral 10 Tablet PR. Inform your doctor if you have ever been diagnosed with kidney or liver problems.