Adrenochrome Monosemicarbazone

Adrenochrome Monosemicarbazone is used in the treatment of bleeding. It works by fastening the process of clot formation and by stopping the bleeding. Adrenochrome Monosemicarbazone should be administered under the supervision of a healthcare professional. You will be watched carefully to make sure you do not have an allergic reaction. You should not take it if you have any known allergy from this injection. The common side effects include injection site reactions such as pain, swelling or redness. Inform your doctor if you are suffering from any severe liver or kidney disease. It may cause injection site reactions like pain or redness. If you miss a dose of this injection, take it as soon as possible. If it is time for your next dose, you can skip the missed dose and continue with your regular schedule. You are not advised to double the dose. Adrenochrome Monosemicarbazone is an oxidative product of adrenaline (chemical messenger) that constricts the blood vessels to reduce the blood flow. This process stops bleeding and also promotes clot formation.

Adrenochrome Monosemicarbazone is indicated in the following conditions : Prevention and treatment of surgical capillary bleedings Prevention and treatment of non-surgical capillary bleedings Control of capillary hemorrhage in dental procedures

Anti-fibrinolytic drugs / Hemostatic Agent

Adrenochrome Monosemicarbazone has a rapid onset of action and reduces normal and pathologic bleeding time by decreasing capillary permeability . It produces capillary hemostasis without exerting any adrenergic effects on the respiratory or cardiovascular system . It does not affect the blood clotting mechanism or blood components . Research suggests it increases capillary resistance and acts directly on the intercellular cement of capillary walls .

Adrenochrome Monosemicarbazone is an oxidation product of adrenaline that constricts blood vessels to reduce blood flow . This process stops bleeding and promotes clot formation by reducing capillary permeability . It works independently of the blood coagulation chemistry and does not affect the vitamin K-prothrombin mechanism .

ট্যাবলেট (Tablet) : ক্যাপিলারি রক্তপাত প্রতিরোধ ও চিকিৎসার জন্য, রোগের তীব্রতা অনুযায়ী প্রতিদিন ৪-১২ টি ট্যাবলেট, Preferably খাবারের এক ঘন্টা আগে সেবন করতে হবে। For the prevention and treatment of capillary bleedings, according to the severity of the case, 4-12 tablets divided over the day, preferably one hour before meals . ইনজেকশন (Injection) : অস্ত্রোপচারের আগে: পূর্ববর্তী সন্ধ্যায় সাধারণত ১.৫-৫ মি.গ্রা. ইন্ট্রামাসকুলার বা সাবকিউটেনিয়াস ইনজেকশন দেওয়া হয়। অস্ত্রোপচারের প্রায় আধা ঘন্টা আগে আরও একটি ইনজেকশন দেওয়া হয় । Prior to surgery: Medication is started on the preceding evening, either orally or by intramuscular or subcutaneous injection of usually 1.5-5 mg. In addition, an injection is given about half an hour before the surgical intervention . প্রিম্যাচিউর ও শিশুদের জন্য সতর্কতা : 5 mg/ml ইনজেকশন প্রস্তুতিতে ডাইপ্রোফাইলিন (90 mg/ml) থাকায়, প্রিম্যাচিউর বেবি, শিশু ও ছোট শিশুদের ডোজ ০.৩ মি.লি.-এর বেশি হওয়া উচিত নয়। Because of the content of diprophylline (90 mg/ml), the dosage of the 5 mg/ml injection preparation to premature babies, infants and young children should not exceed 0.3 ml .

Injection solution should be administered by intramuscular or subcutaneous route; in emergency cases, the injections may be given intravenously . Tablets should be taken orally .

If you miss a dose of Adrenochrome Monosemicarbazone, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Injection site reactions (pain, swelling, redness)

• Due to the content of diprophylline (90 mg/ml), the dose of the 5 mg/ml injection preparation in premature babies, infants, and young children should not exceed 0.3 ml. • Intramuscular injection may be mildly painful. • During pregnancy, the benefits should be weighed against the potential risks to the fetus before use. • Avoid long-term use without medical advice. • Keep out of reach of children. • Store at 2°–25°C in a cool, dry place, protected from light.

There are no known contraindications for this medication . However, it should be avoided in patients with known hypersensitivity to Adrenochrome Monosemicarbazone or any of its components.

No specific drug interaction has been demonstrated . It may be administered simultaneously (but separately) with any type of anesthetic, anticoagulant, vitamin K, or heparin .

[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Adrenochrome Monosemicarbazone. Please consult your doctor.

[CONSULT YOUR DOCTOR] Information regarding the use of Adrenochrome Monosemicarbazone during pregnancy is not available. Please consult your doctor.

[CONSULT YOUR DOCTOR] Information regarding the use of Adrenochrome Monosemicarbazone during breastfeeding is not available. Please consult your doctor.

Due to the diprophylline content in the 5 mg/ml injection preparation, the dosage for premature babies, infants, and young children should not exceed 0.3 ml . The doctor will determine the appropriate dose for other children.

No specific information is available for geriatric use. Use with caution and consult your doctor.

[CONSULT YOUR DOCTOR] There is limited information available on the use of Adrenochrome Monosemicarbazone in patients with kidney disease. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Adrenochrome Monosemicarbazone in patients with liver disease. Please consult your doctor.

No specific information is available on overdose. Excessive doses may cause gastrointestinal discomfort. Consult a doctor in case of overdose.

Store in a cool (2°-25°C), dry place, protected from light. Keep out of reach of children .