Betamethasone valerate Topical

Betamethasone valerate 0.05% Topical is a medium-potency corticosteroid used for the treatment of inflammatory skin conditions including eczema, atopic dermatitis, contact dermatitis, systemic lupus erythematosus, lichen planus, lichen simplex, psoriasis, prurigo nodularis, and plaque psoriasis.

Betamethasone is a corticosteroid with mainly glucocorticoid activity. It prevents and controls inflammation by controlling the rate of protein synthesis, depressing the migration of polymorphonuclear leukocytes and fibroblasts, and reversing capillary permeability and lysosomal stabilisation.

Apply sparingly to the affected area 2-3 times daily. Cream is used for moist skin and ointment for dry skin surfaces.

• Eczema
• Atopic dermatitis
• Contact dermatitis
• Systemic lupus erythematosus
• Lichen planus
• Lichen simplex
• Psoriasis
• Prurigo nodularis
• Plaque psoriasis

Betamethasone is a corticosteroid with mainly glucocorticoid activity. It prevents and controls inflammation by controlling the rate of protein synthesis, depressing the migration of polymorphonuclear leukocytes and fibroblasts, and reversing capillary permeability and lysosomal stabilisation.

Betamethasone valerate blocks the production of inflammatory chemical messengers (prostaglandins) to reduce redness, swelling, and itching of the skin. It controls protein synthesis and depresses the migration of inflammatory cells.

Adults: Apply sparingly to the affected area 2-3 times daily. Cream for moist skin and ointment for dry skin surfaces.

Chronic therapy: Use low potency corticosteroids.

Children: Use lower potency preparations (children have increased BSA/kg, therefore increased systemic absorption).

For external use only. Clean and dry the affected area and apply a thin layer of cream/ointment. Wash hands after application. Avoid contact with eyes.

Important: Avoid medium to very high potency corticosteroids on face, folds, and groin (these areas can increase steroid absorption).

If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double the dose.

• Dermal atrophy
• Local irritation
• Folliculitis
• Hypertrichosis
• Burning
• Dry skin
• Pigmentation changes
• HPA suppression (with higher potency and use >2 weeks)

• Avoid medium to high potency corticosteroids on face, folds, and groin
• Use low potency for chronic therapy
• Chronic topical corticosteroid therapy may interfere with growth and development in children
• Use for less than 2 weeks to reduce local and systemic side effects
• Do not use if underlying infection is present
• Do not use in eyes
• Caution during pregnancy and lactation

• Underlying infection
• Hypersensitivity to betamethasone or any component
• Ophthalmic use

No significant drug interactions are known with other topical medications.

No food-related restrictions (topical application).

[CONSULT YOUR DOCTOR] There are no adequate data on betamethasone valerate ointment use in pregnant women (Category C). Observational studies suggest an increased risk of low birth weight infants with the use of >300 grams of potent topical corticosteroids during pregnancy. Use on the smallest area of skin and for the shortest duration possible.

[CONSULT YOUR DOCTOR] It is not known whether topical corticosteroid use could result in sufficient systemic absorption to produce detectable quantities in human milk. Advise breastfeeding women not to apply ointment directly to nipple and areola to avoid direct infant exposure. Use on the smallest area of skin and for the shortest duration possible.

Use lower potency corticosteroids for children (increased BSA/kg, therefore increased systemic absorption). Chronic topical corticosteroid therapy may interfere with growth and development in children.

No dose adjustment needed for elderly patients, but caution is advised.

Systemic absorption with topical application is minimal, but caution is advised in severe renal or hepatic impairment.

Overuse may cause HPA axis suppression and systemic corticosteroid effects. Consult a doctor if symptoms occur.

Store below 30°C, away from light and moisture. Keep out of reach of children.

Betamethasone valerate 0.05%