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At a glance

Betamethasone valerate 0.05% Topical is a medium-potency corticosteroid used for the treatment of inflammatory skin conditions such as eczema, atopic dermatitis, contact dermatitis, psoriasis, and lichen planus.

Indications
  • Eczema
  • Atopic dermatitis
  • Contact dermatitis
  • Systemic lupus erythematosus
  • Lichen planus
  • Lichen simplex
  • Psoriasis
  • Prurigo nodularis
  • Plaque psoriasis
Pharmacology

Betamethasone is a corticosteroid with mainly glucocorticoid activity. It prevents and controls inflammation by controlling the rate of protein synthesis, depressing the migration of polymorphonuclear leukocytes and fibroblasts, and reversing capillary permeability and lysosomal stabilisation.

Dosage

Adults: Apply sparingly to the affected area 2-3 times daily. Cream for moist skin and ointment for dry skin surfaces.

Chronic therapy: Use low potency corticosteroids.

Children: Use lower potency preparations (children have increased BSA/kg, therefore increased systemic absorption).

Side effects
  • Dermal atrophy
  • Local irritation
  • Folliculitis
  • Hypertrichosis
  • Burning
  • Dry skin
  • Pigmentation changes
  • HPA suppression (with higher potency and use >2 weeks)
Use in pregnancy

[CONSULT YOUR DOCTOR] There are no adequate data on betamethasone valerate ointment use in pregnant women (Category C). Observational studies suggest an increased risk of low birth weight infants with the use of >300 grams of potent topical corticosteroids during pregnancy. Use on the smallest area of skin and for the shortest duration possible.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Avoid medium to high potency corticosteroids on face, folds, and groin
  • Use low potency for chronic therapy
  • Chronic topical corticosteroid therapy may interfere with growth and development in children
  • Use for less than 2 weeks to reduce local and systemic side effects
  • Do not use if underlying infection is present
  • Do not use in eyes
  • Caution during pregnancy and lactation
Overdose effects

Overuse may cause HPA axis suppression and systemic corticosteroid effects. Consult a doctor if symptoms occur.

Storage conditions

Store below 30°C, away from light and moisture. Keep out of reach of children.

Betamethasone valerate Topical — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.