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Generic

Cefoperazone

4 brands available in the market

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BrandCompanyFormPrice/unit
Cefoject IM/IV1gm/vialEskayefInjection৳ 250
Cefopen 1 gm IM/IV1gm/vialSquare Pharmaceuticals PLC.Injection৳ 250
Cefopen 2gm Inj2gm/vialSquare Pharmaceuticals PLC.Injection৳ 400
Cefaking1gm/vialDrug International Ltd.Injection

At a glance

Cefoperazone — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Cefoperazone is an antibiotic medicine used to treat bacterial infections in your body. It is effective in infections of the lungs (eg. pneumonia), ear, urinary tract, skin and soft tissues, bones and joints, blood, and heart. It is also used to prevent infections during surgery. Cefoperazone fights and stops the growth of many types of bacteria. This helps to improve your symptoms and cure the underlying infection. It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional. Your doctor will decide the correct dose for you. You should use this medicine regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The most common side effects of this medicine include diarrhea and changes in liver function tests and blood counts. Some people may develop temporary redness or pain at the site of injection. These side effects are usually mild but let your doctor know if they bother you or last more than a few days. Avoid consuming alcohol while taking this medicine as it may cause increased side effects. Before using it, you should tell your doctor if you are allergic to any antibiotics, and if you have any liver or kidney problems. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it. Cefoperazone is an antibiotic. It kills the bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

Indications

• Bacterial infections

Mechanism of action

Cefoperazone binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.

Dosage

Adult Dose: Parenteral Susceptible infections Adult: As sodium: 2-4 g daily in 2 divided doses, increased to 12 g daily in 2-4 divided doses for severe infections given as deep IM or IV infusion. Hepatic impairment: Max for hepatic impairment or biliary obstruction: 4 g daily. W/ renal impairment: 1-2 g daily. Renal Dose: Renal impairment: W/ hepatic impairment: 1-2 g daily.

Administration

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Missed dose

If you miss a dose of Cefoperazone, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Side effects

Common: • Increased liver enzymes • Allergic reaction • Anemia (low number of red blood cells) • Diarrhea

Precautions & warnings

[SAFE] Cefoperazone does not usually affect your ability to drive. Your doctor has prescribed Cefoperazone to cure your infection and improve your symptoms. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection harder to treat. Discontinue Cefoperazone and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing. Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools. Avoid consuming alcohol while taking Cefoperazone as it may cause increased side effects.

Contraindications

Hypersensitivity to cephalosporin.

Drug interactions

Disulfiram-like reaction with alcohol. Potentiates anticoagulants. Potentially Fatal: Enhances nephrotoxicity by aminoglycosides and furosemide.

Food interactions

[UNSAFE] Consuming alcohol while taking Cefoperazone may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).

Use in pregnancy

[SAFE IF PRESCRIBED] Cefoperazone is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Use in lactation

[SAFE IF PRESCRIBED] Cefoperazone is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. Avoid prolonged use of Cefoperazone, since it may have possible effects such as rash and diarrhea.

Renal / hepatic impairment

[SAFE IF PRESCRIBED] Cefoperazone is safe to use in patients with kidney disease. No dose adjustment of Cefoperazone is recommended. [CONSULT YOUR DOCTOR] There is limited information available on the use of Cefoperazone in patients with liver disease. Please consult your doctor.

Common questions

Scar on face due to bacterial infections Pic is not clear, plz visit for proper opinion I have a history of recurring yeast and bacterial vaginosis infections. Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days I suffering from bacterial infections in my shaving area or too much acne problem. Fudic cream twice a day My child verry high cough and fever in cold sesion try to much doctor but result is no . It's will be countiue cough and fever it's good to be only antiboitic Antibiotics are required if bacterial infections. Consult child specialist What are use mega-cv dry syrup Child are not drinking milk Mega CV is an antibiotic used to treat bacterial infections Sir which medication can we use to fast healing the wound such as minor cut,bacterial infections just apply Neomycin cream locally I get infections around my private parts and also near my toes It's basically fungus or bacterial infection Dear Mr PATIENT need to check your lesions before prescribing any medications, post a high quality image of the lesion with a good resolution.

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.
Cefoperazone — দাম, ব্যবহার, ডোজ ও পার্শ্বপ্রতিক্রিয়া | oshudhkosh