Chloramphenicol 0.5% Eye drops

Chloramphenicol 0.5% Eye drops is an antibiotic that fights bacteria. It is used to treat infections of the eye caused by bacteria. It works by killing the bacteria that cause these problems. Chloramphenicol 0.5% Eye drops helps to improve your symptoms and cure the underlying infection. Follow your doctor's instructions precisely for administering this medicine in the eye. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. It is effective in killing many types of bacteria. However, it will not work for other types of eye infections (e.g. viral) and therefore, should only be used if prescribed by your doctor. Unnecessary use of any antibiotic can lead to a decrease in its effectiveness in the future. Commonly seen side effects seen with this medicine include temporary stinging in eyes and blurred vision after administration. Consult your doctor if these side effects persist or if your condition worsens. Pregnant and breastfeeding mothers should consult their doctor before using it. Contact lenses should not be worn while you are using this medicine or while you have the bacterial eye infection. This medicine should not be used for longer than five days without consulting your doctor.

Chloramphenicol 0.5% Eye drops is an antibiotic which stops the growth of bacteria that cause eye infections. It does so by preventing synthesis of essential proteins required by bacteria to carry out vital functions. This does not directly kill the bacteria, but prevents them from increasing in numbers, and eventually clears up the eye infection.

• Bacterial conjunctivitis
• Bacterial eye infections

Chloramphenicol inhibits bacterial protein synthesis by binding to 50s subunit of the bacterial ribosome, thus preventing peptide bond formation by peptidyl transferase. It has both bacteriostatic and bactericidal action against H. influenzae, N. meningitidis and S. pneumoniae.

Chloramphenicol inhibits bacterial protein synthesis by binding to 50s subunit of the bacterial ribosome, thus preventing peptide bond formation by peptidyl transferase.

Adult Dose (Ophthalmic): Instill 1 drop every 2 hours. Increase dosage interval upon improvement. Continue treatment for at least 48 hours after complete healing. Reduce dose once symptoms are controlled or apply a 1% ointment 3-4 times daily.

Hepatic Impairment: Dose reduction may be required.

Renal Impairment: Dose reduction may be required.

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid.

If you miss a dose of Chloramphenicol 0.5% Eye drops, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common Side Effects:

• Stinging in the eyes
• Blurred vision
• Eye irritation
• Redness

Serious Side Effects (Rare): Allergic reactions, bone marrow depression (with systemic absorption).

• [UNSAFE] Chloramphenicol 0.5% Eye drops may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.
• You have been prescribed Chloramphenicol 0.5% Eye drops for the treatment of bacterial infections of the eye. Do not skip any doses and finish the full course of treatment even if you feel better.
• Do not touch the tip to any surface, or to your eye, to avoid contamination.
• Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
• You should continue using the medicine for 48 hours after your symptoms have cleared up. However, do not use for longer than five days without consulting your doctor.
• Do not wear contact lenses until your infection clears up.
• Throw away any medicine left at the end of the 5 day course.

• History of hypersensitivity or toxic reaction to the drug
• Herpes simplex and other viral conditions of the eye or ear
• Mycosis (fungal infections)

Decreased effects of iron and vitamin B12 in anemic patients. Phenobarbitone and rifampin reduce efficacy of chloramphenicol. Impairs the action of oral contraceptives. Increases the effect of oral anticoagulants, oral hypoglycemic agents, phenytoin. Avoid concomitant administration with drugs that depress bone marrow function.

No food interactions found or established.

[CONSULT YOUR DOCTOR] Chloramphenicol 0.5% Eye drops may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Chloramphenicol 0.5% Eye drops is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Limited information is available regarding safety and efficacy in pediatric patients. Use as advised by a physician.

Limited information is available regarding dose adjustment for elderly patients.

No information is available on use in kidney or liver problems.

Information on overdosage is not available. Consult a physician if overdose is suspected.

Keep in a cool and dry place, away from light & keep out of the reach of children.

Chloramphenicol 0.5%