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At a glance

Chloramphenicol 0.5% Eye drops is an antibiotic that fights bacteria. It is used to treat infections of the eye caused by bacteria.

Indications
  • Bacterial conjunctivitis
  • Bacterial eye infections
Pharmacology

Chloramphenicol inhibits bacterial protein synthesis by binding to 50s subunit of the bacterial ribosome, thus preventing peptide bond formation by peptidyl transferase. It has both bacteriostatic and bactericidal action against H. influenzae, N. meningitidis and S. pneumoniae.

Dosage

Adult Dose (Ophthalmic): Instill 1 drop every 2 hours. Increase dosage interval upon improvement. Continue treatment for at least 48 hours after complete healing. Reduce dose once symptoms are controlled or apply a 1% ointment 3-4 times daily.

Hepatic Impairment: Dose reduction may be required.

Renal Impairment: Dose reduction may be required.

Side effects

Common Side Effects:

  • Stinging in the eyes
  • Blurred vision
  • Eye irritation
  • Redness

Serious Side Effects (Rare): Allergic reactions, bone marrow depression (with systemic absorption).

Use in pregnancy

[CONSULT YOUR DOCTOR] Chloramphenicol 0.5% Eye drops may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Precautions & warnings
  • [UNSAFE] Chloramphenicol 0.5% Eye drops may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.
  • You have been prescribed Chloramphenicol 0.5% Eye drops for the treatment of bacterial infections of the eye. Do not skip any doses and finish the full course of treatment even if you feel better.
  • Do not touch the tip to any surface, or to your eye, to avoid contamination.
  • Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
  • You should continue using the medicine for 48 hours after your symptoms have cleared up. However, do not use for longer than five days without consulting your doctor.
  • Do not wear contact lenses until your infection clears up.
  • Throw away any medicine left at the end of the 5 day course.
Overdose effects

Information on overdosage is not available. Consult a physician if overdose is suspected.

Storage conditions

Keep in a cool and dry place, away from light & keep out of the reach of children.

Chloramphenicol 0.5% Eye drops — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.