osudhkosh

Generic

Clotrimazole 1% Eye prep

3 brands available in the market

At a glance

Clotrimazole 1% Eye prep is an antifungal medication used for the treatment of fungal keratitis and fungal eye infections.

Description

Clotrimazole is a broad-spectrum antifungal agent that is used for the treatment of dermal infections caused by various species of pathogenic dermatophytes, yeasts, and Malassezia furfur. The primary action of clotrimazole is against dividing and growing organisms. Clotrimazole inhibits ergosterol synthesis, resulting in abnormal cellular permeability. This inhibits fungal growth. Clotrimazole Eye prep is used for the treatment of fungal eye infections and fungal keratitis.

Indications
  • Fungal keratitis
  • Fungal eye infections
Therapeutic class

Antifungals (Ophthalmic)

Pharmacological class

Topical Antifungal (Ophthalmic Preparation)

Pharmacology

Clotrimazole kills fungi and yeasts by interfering with their cell membranes. It works by stopping the production of ergosterol, which is an essential component of fungal cell membranes resulting in increased membrane permeability and leakage of essential constituents of the fungal cells.

Mechanism of action

Clotrimazole is a broad-spectrum antifungal which binds to phospholipids in the cell membrane altering cell wall permeability causing a loss in essential intracellular elements.

Dosage

Adult Dose (Ophthalmic): Apply thinly and evenly to the conjunctival sac every 4 hours daily.

Administration

This medicine is for ophthalmic use only. Apply a small amount to the conjunctival sac every 4 hours. Shake well before use. Do not touch the dropper tip to the eye or any other surface.

Missed dose

If you miss a dose of Clotrimazole 1% Eye prep, use it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose. Do not double the dose.

Side effects

This drug is generally well tolerated.

Precautions & warnings
  • For ophthalmic use only.
  • If local intolerance develops, consider withdrawal of the medicine and institution of appropriate therapy.
  • Caution during pregnancy and lactation.
  • Not recommended in children under 3 years.
Contraindications
  • Hypersensitivity.
Drug interactions

Antagonism with polyene antibiotics.

Food interactions

No food interactions have been found or established.

Use in pregnancy

Limited information is available regarding the use of Clotrimazole 1% Eye prep during pregnancy. Consult your doctor before use.

Use in lactation

Limited information is available regarding the use of Clotrimazole 1% Eye prep during breastfeeding. Consult your doctor before use.

Pediatric use

Not recommended in children under 3 years.

Geriatric use

Limited information is available regarding dose adjustment for elderly patients.

Renal / hepatic impairment

For topical/ophthalmic use, no dose adjustment is required in renal or hepatic impairment.

Overdose effects

Information on overdosage is not available. Consult a physician if overdose is suspected.

Storage conditions

Store in a cool and dry place, away from light and out of reach of children.

Chemical structure

Clotrimazole 1%

Common questions

What is Clotrimazole 1% Eye prep used for?
It is used for fungal keratitis and fungal eye infections.
How to use Clotrimazole 1% Eye prep?
Apply a small amount to the conjunctival sac every 4 hours.
What are the side effects of Clotrimazole 1% Eye prep?
This drug is generally well tolerated.
Can Clotrimazole 1% Eye prep be used during pregnancy?
Limited information is available. Consult your doctor.
Who should not use Clotrimazole 1% Eye prep?
Patients with hypersensitivity or children under 3 years.
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.