Generic
Cranberry
14 brands available in the market
At a glance
Cranberry is a North American herb commonly used for the treatment and prevention of urinary tract infections (UTIs) and kidney stone management.
Description
Cranberry (Vaccinium macrocarpon) is a native North American plant commonly used for reduction in urinary tract infections (UTIs) occurrence and kidney stone management. Cranberry reduces the need for repeated antibiotic use in the treatment of recurrent urinary tract infection. Bacterial adherence to mucosal surfaces is generally considered to be the initial event in the pathogenesis of most infectious diseases due to bacteria in humans such as UTIs. Cranberry inhibits adherence of bacteria to the lining of the urinary bladder and urethra. At higher dose it also works as a urinary antiseptic and reduces incidence of stone formation. Recent publications show as much as 65% reduction in UTI with cranberry consumption leading to reduced use of antibiotics and reduction in the number of incidences of recurrent cystitis.
Indications
- Treatment and prevention of urinary tract infection
- Kidney stones
Therapeutic class
Herbal and Nutraceuticals
Pharmacological class
Herbal Supplement (Urinary Health)
Pharmacology
Cranberry inhibits adherence of bacteria to the lining of the urinary bladder and urethra. At higher dose it also works as a urinary antiseptic and reduces incidence of stone formation. Recent publications show as much as 65% reduction in UTI with cranberry consumption leading to reduced use of antibiotics and reduction in the number of incidences of recurrent cystitis.
Mechanism of action
Cranberry PACs (proanthocyanidins) inhibit bacterial adhesion to the bladder and urethral walls, which is the primary cause of UTIs.
Dosage
Syrup Dose: 2-4 spoonful (10-20 mL) daily before meal or as directed by the physician. Can be diluted in a glass of water if required. Shake well before use.
Capsule Dose: 1-3 capsules daily or as advised by the physician.
Administration
Syrup: 2-4 spoonful (10-20 mL) daily before meal or as directed. Can be diluted in a glass of water if required. Shake well before use.
Capsules: 1-3 capsules daily or as advised by the physician.
Missed dose
If you miss a dose of Cranberry, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose. Do not double the dose.
Side effects
Well tolerated in recommended dose. Occasionally diarrhea or mild gastrointestinal upset may occur at high dose.
Precautions & warnings
- Consult a physician before starting any new supplement.
- Do not exceed the recommended dose.
- Caution in renal insufficiency or risk of uric acid/calcium oxalate stones.
- No known restrictions during pregnancy or lactation, but consult your doctor before use.
Contraindications
- Renal insufficiency
- Potential for developing uric acid or calcium oxalate stones
Drug interactions
No known interactions with antibiotics or other drugs. Cranberry enhances vitamin B12 absorption, which is useful for patients taking omeprazole.
Food interactions
Can be taken with or without food (syrup is recommended before meals).
Use in pregnancy
No known restrictions during pregnancy. Consult your doctor before use.
Use in lactation
No known restrictions during lactation. Consult your doctor before use.
Pediatric use
Pediatric dosage should be determined by a physician.
Geriatric use
Limited information is available regarding dose adjustment for elderly patients.
Renal / hepatic impairment
[CAUTION] Caution in renal insufficiency or risk of uric acid/calcium oxalate stones.
Overdose effects
Information on overdosage is not available. Consult a physician if overdose is suspected.
Storage conditions
Store in a cool and dry place, away from light and moisture. Keep out of reach of children.
Chemical structure
Cranberry Extract