Disodium Hydrogen Phosphate Dodecahydrate 24% + Sodium Dihydrogen Phosphate Dihydrate 54.22%

Sodium phosphate can be used in the management of hypophosphataemia. It also acts as a mild osmotic laxative when given orally as dilute solutions or by the rectal route. Phosphate enemas or concentrated oral solutions are used for bowel cleansing before surgery or endoscopy procedures.

• Occasional constipation
• Bowel cleansing (before surgery, X-ray, or endoscopic examination)

Sodium phosphate can be used in the management of hypophosphataemia. It also acts as a mild osmotic laxative when given orally as dilute solutions or by the rectal route.

Sodium phosphate draws water into the bowel, creating an osmotic effect that stimulates peristalsis and helps cleanse the colon.

Adult (Colon cleansing - Early morning procedure): First dose at 7 AM, second dose at 7 PM (each dose: 15 mL solution + 250 mL clear liquid, repeat 3 times within 20 minutes).
Adult (Constipation - ≥12 years): 20-45 mL.
Child (10-11 years): 10-20 mL.
Child (5-9 years): 5-10 mL.

Drink at least 3 glasses (approximately 250 mL each) of clear liquids between doses. Drink plenty of fluids to prevent dehydration.

If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose.

Common: Bloating (31-41%), nausea (26-30%), abdominal pain (23-25%), vomiting (4-9%).
Other: Dizziness, headache, seizures, renal impairment, increased BUN/creatinine, acute renal failure, acute phosphate nephropathy, anaphylaxis, rash, pruritus, urticaria, throat tightness, bronchospasm, dyspnea.

Caution in severe renal insufficiency (CrCl <30 mL/min), CHF, ascites, unstable angina, gastric retention, ileus, acute bowel obstruction, pseudo-obstruction, severe chronic constipation, bowel perforation, acute colitis, toxic megacolon, gastric bypass surgery, hypomotility syndrome.

CHF, renal failure or clinically significant impaired renal function, congenital or acquired megacolon, bowel/GI obstructions, ascites, perforation of ileus, active inflammatory bowel disease, allergy/hypersensitivity to sodium phosphate.

Calcium channel blockers, diuretics, ACE inhibitors, ARBs, NSAIDs, lithium: May affect electrolyte levels.
Polyethylene glycol (PEG) preparations: Concurrent use may be dangerous; not recommended.

Take clear liquids (water, tea/coffee without milk, carbonated/non-carbonated soft drinks, fruit juices) - not colored red or purple. Avoid alcohol.

Use during pregnancy is not recommended (potential harm to fetus from phosphate absorbed across the placenta).

Use during lactation is not recommended (potential harm to infant from phosphate excreted in breast milk).

Not to be taken by children under 5 years of age.

Use with extreme caution in the elderly, frail, or debilitated patients.

Caution in renal impairment; dose adjustment may be needed.

Overdose may cause electrolyte imbalance, dehydration, cardiac arrhythmias. Seek medical attention.

Store in a cool and dry place, protected from light. Keep out of reach of children.

Disodium Hydrogen Phosphate Dodecahydrate + Sodium Dihydrogen Phosphate Dihydrate