Phosphoprep

• Occasional constipation
• Bowel cleansing (before surgery, X-ray, or endoscopic examination)

Sodium phosphate can be used in the management of hypophosphataemia. It also acts as a mild osmotic laxative when given orally as dilute solutions or by the rectal route.

Adult (Colon cleansing - Early morning procedure): First dose at 7 AM, second dose at 7 PM (each dose: 15 mL solution + 250 mL clear liquid, repeat 3 times within 20 minutes).
Adult (Constipation - ≥12 years): 20-45 mL.
Child (10-11 years): 10-20 mL.
Child (5-9 years): 5-10 mL.

Common: Bloating (31-41%), nausea (26-30%), abdominal pain (23-25%), vomiting (4-9%).
Other: Dizziness, headache, seizures, renal impairment, increased BUN/creatinine, acute renal failure, acute phosphate nephropathy, anaphylaxis, rash, pruritus, urticaria, throat tightness, bronchospasm, dyspnea.

Use during pregnancy is not recommended (potential harm to fetus from phosphate absorbed across the placenta).

Caution in severe renal insufficiency (CrCl <30 mL/min), CHF, ascites, unstable angina, gastric retention, ileus, acute bowel obstruction, pseudo-obstruction, severe chronic constipation, bowel perforation, acute colitis, toxic megacolon, gastric bypass surgery, hypomotility syndrome.

Overdose may cause electrolyte imbalance, dehydration, cardiac arrhythmias. Seek medical attention.

Store in a cool and dry place, protected from light. Keep out of reach of children.