Generic
Etomidate
1 brands available in the market
At a glance
Etomidate is a general anesthetic used for major surgical procedures. It allows procedures to be carried out without pain and distress.
Description
Etomidate is a general anesthetic. It is used in major surgical procedures. It allows the procedures to be carried out without pain and distress. It is administered under the supervision of a healthcare professional.
Etomidate causes loss of consciousness which is reversible. You may be monitored during the complete procedure to observe changes in vital signs such as blood pressure, pulse rate, heartbeat and ventilation.
Indications
- General Anaesthesia: Used for induction of anaesthesia in surgical procedures.
Therapeutic class
General Anesthetic
Pharmacological class
Sedative/Hypnotic (Anesthetic)
Pharmacology
Etomidate is a carboxylated imidazole. It is a sedative and hypnotic agent used commonly for induction anaesthesia.
Mechanism of action
Etomidate is a general anaesthetic. It works by causing reversible loss of consciousness. This allows surgical procedures to be carried out without pain and distress.
Dosage
Adult Dose (IV):
- General Anesthesia Induction: 0.3-0.6 mg/kg IVP over 30-60 sec.
Child Dose (>=10 years):
- General Anesthesia Induction: 0.3-0.6 mg/kg IVP over 30-60 sec.
Administration
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Missed dose
If you miss a dose of Etomidate, please consult your doctor.
Side effects
Common Side Effects:
- Headache
- Fatigue
- Weakness
- Fever
- Muscle pain
Precautions & warnings
Precautions:
- Etomidate may affect your ability to drive; may cause sleepiness and impair ability to think or react.
- Used only in a hospital setting.
- Inform doctor if you are pregnant or suffering from liver disease.
- Safe to use in kidney disease.
- Safe for breastfeeding mothers (breastfeeding can be resumed after recovery from anesthesia).
Contraindications
Contraindications:
- Hypersensitivity
- Reduced or at risk of reduced adrenocortical function
- Porphyria
Drug interactions
Drug Interactions:
- Antipsychotics, sedatives or opioids: May interact.
- Calcium-channel blockers: May interact.
Food interactions
Food Interactions: It is not known whether it is safe to consume alcohol with Etomidate. Consult your doctor.
Use in pregnancy
Use in Pregnancy: Etomidate may be unsafe; animal studies have shown harmful effects on the developing baby.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Etomidate is probably safe; breastfeeding can be resumed after recovery from anesthesia.
Pediatric use
Pediatric Use: Dose for children >=10 years provided above.
Geriatric use
Geriatric Use: No specific dosage adjustment is necessary for elderly patients.
Renal / hepatic impairment
Renal Impairment: Safe to use; no dose adjustment needed.
Hepatic Impairment: Use with caution; dose adjustment may be needed.
Overdose effects
Overdose: Overdose may cause excessive sedation, respiratory depression; symptomatic treatment.
Storage conditions
Storage: Store as per manufacturer's instructions.
Chemical structure
Etomidate