Fructose 10%

Introduction: Fructose 10% is an intravenous carbohydrate nutrient used for caloric feeding and fluid replacement in diabetic patients. It is converted to liver glycogen and metabolized more rapidly than dextrose without requiring insulin, thus may be used in diabetic patients.

How it works: Fructose is converted to glycogen in the liver and metabolized rapidly without requiring insulin. It is a better 'nitrogen sparer' than glucose.

Important Information: It should not exceed 0.5-1 g/kg body weight per hour. The usual recommended flow rate for adult is 30-75 drops per minute infused intravenously.

• Carbohydrate nutrient in diabetic patients
• Fluid replacement
• Caloric feeding

Intravenous Nutrition

Carbohydrate

Fructose is used intravenously as a carbohydrate nutrient. It is converted to liver glycogen and metabolized more rapidly than dextrose without requiring insulin and thus may be used in diabetic patients. Fructose is indicated in patients requiring fluid replacement and caloric feeding. It is a better 'nitrogen sparer' than glucose.

Fructose is converted to glycogen in the liver and metabolized rapidly without requiring insulin, producing energy.

Adult Dose:

• Should not exceed 0.5-1 g/kg body weight per hour.
• Usual recommended flow rate: 30-75 drops per minute infused intravenously.

* Use as directed by the registered physician

Intravenous (IV) infusion. Check infusion set and solution prior to use. Do not use if the solution is cloudy, contains particles, or after expiry date.

If you miss a dose, consult your doctor.

Common Side Effects:

• Lactic acidosis
• Hyperuricemia
• Rapid infusion results in facial flushing, abdominal pain and sweating

Precautions:

• Should not be given to patients with hereditary fructose intolerance.
• Should be given with caution to patients with impaired kidney function or severe liver damage.
• Infusion should be immediately discontinued if rigor arises for any reason during the process.

Contraindications:

• Certain inborn errors of fructose metabolism
• Methyl alcohol poisoning
• Hyperuricemia
• Liver failure
• Lactic acidosis

Drug Interactions: No significant interactions found.

Food Interactions: No interaction found/established.

Use in Pregnancy: Consult your doctor before use during pregnancy.

Use in Lactation: Consult your doctor before use during lactation.

Pediatric Use: Use as per doctor's advice for children.

Geriatric Use: Use as per doctor's advice for elderly patients.

Renal & Hepatic Impairment: Should be given with caution to patients with impaired kidney function or severe liver damage.

Overdose: Overdose may cause lactic acidosis and hyperuricemia. Discontinue infusion and provide symptomatic treatment.

Storage: Store below 30°C, away from light and moisture. Keep out of reach of children.

Fructose 10% Injection