Generic
Iron Hydroxide Polymaltose
9 brands available in the market
At a glance
Iron Hydroxide Polymaltose is an iron replacement product used for the treatment of iron deficiency anaemia and anaemia due to chronic kidney disease.
Description
Iron Hydroxide Polymaltose is a water soluble, macro-molecular complex of iron (III) hydroxide and isomaltose. It replenishes the iron stores in the body and helps in the formation of new red blood cells and hemoglobin. Iron is essential for hemoglobin formation, which transports oxygen. It is an oral iron supplement that is well-tolerated and effective.
Indications
- Iron deficiency anaemia
- Anaemia due to chronic kidney disease
Therapeutic class
Oral Iron preparations
Pharmacological class
Iron Polymaltose Complex
Pharmacology
Iron polymaltose is a water soluble, macro-molecular complex of iron (III) hydroxide and isomaltose. It is used in the treatment of iron-deficiency anaemia. Iron is an essential component in the formation of hemoglobin; adequate amounts of iron are necessary for effective erythropoiesis. It replaces iron stores found in hemoglobin, myoglobin, and enzymes and works to transport oxygen via hemoglobin.
Mechanism of action
Replaces depleted iron stores in the bone marrow for haemoglobin synthesis, correcting iron deficiency anaemia.
Dosage
Adult Dose (Oral):
- 10 ml once or twice daily (depending on extent of iron deficiency)
Child Dose (Oral):
- 6-12 years: 10 ml daily
- 2-6 years: 5 ml daily
- Premature infants & Infants: 3.33 mg elemental iron/kg (0.06 ml drops/kg) daily
Administration
Take in the dose and duration as advised by your doctor; check label for directions; measure with a measuring cup; take on empty stomach; shake well before use.
Missed dose
If you miss a dose, please consult your doctor.
Side effects
Common Side Effects:
- Nausea
- Dark colored stool
- Diarrhea
- Constipation
- Injection site reactions (pain, swelling, redness)
Precautions & warnings
Precautions:
- It is not known whether Iron Hydroxide Polymaltose alters ability to drive; do not drive if you experience symptoms affecting concentration and reaction
- Tell doctor if you have rheumatoid arthritis, asthma or other allergies, high blood pressure or liver problems
- Tests to check blood cells and iron levels will be needed
- Limit alcohol during treatment
- Caution in kidney or liver disease
Contraindications
Contraindications:
- Hypersensitivity or intolerance to iron
- Iron overload in the body
- Anaemia not caused by iron deficiency
- Disturbances in iron utilisation (thalassemia)
- Patients receiving repeated blood transfusion
- Pregnancy (1st trimester)
Drug interactions
Drug Interactions:
- Concurrent use with psychotropic drugs may worsen constipation
- Increased systemic side effects with concomitant ACE inhibitors and parenteral iron administration
Food interactions
Food Interactions: It is unsafe to consume alcohol with Iron Hydroxide Polymaltose.
Use in pregnancy
Use in Pregnancy: May be unsafe; animal studies have shown harmful effects; doctor will weigh benefits and risks; contraindicated in 1st trimester.
Use in lactation
Use in Lactation: Safe during breastfeeding; does not pass into breastmilk in significant amount and is not harmful to baby.
Pediatric use
Pediatric doses provided above.
Geriatric use
No specific data for elderly; however caution advised.
Renal / hepatic impairment
Renal Impairment: Caution in kidney disease; dose adjustment may be needed.
Hepatic Impairment: Caution in liver disease; dose adjustment may be needed; decompensated liver cirrhosis contraindicated.
Overdose effects
Overdose: Epigastric pain, diarrhea, vomiting, metabolic acidosis, convulsions may occur; seek emergency medical attention; initially give emetic and then gastric lavage.
Storage conditions
Store in a cool and dry place, protected from light; keep out of reach of children.
Chemical structure
Iron Hydroxide Polymaltose