osudhkosh

Generic

Glucose (Dextrose) Anhydrous + Potassium Chloride + Tri-sodium citrate + Sodium chloride (ORS)

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At a glance

ORS is used to restore fluid and electrolyte balance caused by diarrhea, vomiting and dehydration.

Description

Introduction: ORS is an oral rehydration saline used to restore fluid and electrolyte balance caused by diarrhea, vomiting and dehydration.

How it works: Potassium chloride is a major cation of intracellular fluid which helps in nerve impulse conduction, muscle contraction and acid-base balance. Sodium chloride is the major extracellular cation which controls electrolyte and fluid balance. Dextrose acts as a source of energy and enhances sodium and water absorption from the intestine.

Important Information: Take specific amount of saline after each loose stool or vomiting. Use reconstituted saline within 6 hours.

Indications
  • Diarrhea
  • Dehydration
  • Vomiting
  • Fluid and Electrolytes imbalance
Therapeutic class

Oral Rehydration Preparations

Pharmacological class

Electrolyte Solution

Pharmacology

Potassium chloride is a major cation of the intracellular fluid. It plays an active role in the conduction of nerve impulses in the heart, brain and skeletal muscle; contraction of cardiac skeletal and smooth muscles; maintenance of normal renal function, acid-base balance, carbohydrate metabolism and gastric secretion. Sodium chloride is the major extracellular cation important in electrolyte and fluid balance, osmotic pressure control and water distribution. Dextrose is a monosaccharide used as a source of calories and water for hydration and enhances sodium and water absorption from the intestine.

Mechanism of action

ORS prevents dehydration by enhancing sodium and water absorption from the intestine and restores lost electrolytes.

Dosage

Adults:

  • 200-400 ml of prepared saline after each loose stool or vomiting
  • Daily dose equivalent to patient's fluid requirement

Children above 10 years:

  • 200-400 ml after each loose stool or vomiting

Children 2-10 years:

  • 100-200 ml after each loose stool or vomiting

Children under 2 years:

  • 50-100 ml (10-20 spoonful) after each loose stool or vomiting
Administration

Oral powder. Dissolve in clean water as per instructions. Use reconstituted saline within 6 hours.

Missed dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and follow your regular schedule.

Side effects

Side Effects:

  • No significant side effects
Precautions & warnings

Precautions:

  • Depressed renal function may require parenteral fluids
  • Consult doctor in case of severe continuing diarrhea
  • Use reconstituted saline within 6 hours
Contraindications

Contraindications:

  • Known hypersensitivity
Drug interactions

Drug Interactions: No significant interactions known.

Food interactions

Food Interactions: No interaction found/established.

Use in pregnancy

Use in Pregnancy: Safe to use during pregnancy.

Pregnancy Category: NA — always consult a doctor before taking during pregnancy.

Use in lactation

Use in Lactation: Safe to use during breastfeeding.

Pediatric use

Pediatric Use: Specific dosage available for all age groups.

Geriatric use

Geriatric Use: Use as per doctor's advice for elderly patients.

Renal / hepatic impairment

Renal Impairment: Caution in depressed renal function. May require parenteral fluids.

Hepatic Impairment: No known restrictions.

Overdose effects

Overdose: Excessive intake may cause electrolyte imbalance. Consult your doctor.

Storage conditions

Storage: Store in a cool and dry place. Use reconstituted saline within 6 hours.

Chemical structure

ORS Powder

Common questions

Q1: What is ORS used for?
It is used to restore fluid and electrolyte balance caused by diarrhea, vomiting and dehydration.
Q2: How to prepare ORS?
Dissolve in clean water as per instructions and use within 6 hours.
Q3: How much ORS to give to children?
Under 2 years: 50-100 ml, 2-10 years: 100-200 ml, above 10 years: 200-400 ml after each stool.
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.