Generic
Povidone Iodine 5% Topical
17 brands available in the market
At a glance
Povidone Iodine 5% Topical is an antiseptic and disinfectant used for treatment and prevention of wound infections. It kills harmful microbes and controls their growth, preventing infections on the affected area.
Description
Povidone-iodine is an iodophore with powerful broad-spectrum germicidal activity against bacteria, viruses, fungi, protozoa, and spores. It oxidizes cell constituents and iodinates proteins, inactivating them. The 5% formulation in ointment and powder forms is effective for treatment of skin infections.
Indications
- Primary and secondary topical infections
- Infected surgical incisions
- Infected decubitus or stasis ulcers
- Pyodermas
- Secondarily infected dermatoses
- Infected traumatic lesions
- Minor cuts, wounds, abrasions
- Prevention of infection in burns
Therapeutic class
Iodine compounds (Anti-septic Preparations)
Pharmacological class
Topical Antiseptic (Povidone-Iodine)
Pharmacology
Povidone-iodine slowly releases elemental iodine, providing prolonged germicidal activity. The 5% formulation in ointment and powder forms is effective against a broad range of microorganisms on the skin and helps prevent infections.
Mechanism of action
Prevents infection by killing harmful microorganisms.
Dosage
Adult Dose (Topical):
- Ointment (treatment of infection): Apply once or twice daily or at dressing changes, for a maximum of 14 days
- Ointment (prevention of infection): Apply once or twice a week as long as necessary
- Powder: Apply a light dusting to the affected area as needed
Administration
- Check the label before use
- Clean and dry the affected area before application
- Apply directly to the affected area
- May be covered with dressing or bandage if needed
Missed dose
If you miss a dose, apply it as soon as you remember; skip if it's almost time for next application; do not double the dose.
Side effects
Side Effects:
- No common side effects seen
- Skin and mucous membrane irritation (rare)
Precautions & warnings
- For deep or puncture wounds or serious burns, consult a physician
- If redness, irritation, swelling, or pain persists or infection occurs, discontinue use
- Avoid regular use in thyroid disorders (nodular colloid goitre, endemic goitre, Hashimoto's thyroiditis) or on lithium therapy
- Not for use in children under 2 years
- Caution when regular applications to broken skin are made to patients with pre-existing renal insufficiency
Contraindications
- Hypersensitivity to povidone iodine or any ingredient
- Regular use in thyroid disorders
- Lithium therapy
- Children under 2 years
Drug interactions
- Concurrent use with lithium therapy may exhibit hypothyroid effect
Food interactions
Not food-related (topical use).
Use in pregnancy
Use in Pregnancy: May be unsafe during pregnancy; animal studies have shown harmful effects; consult your doctor.
Use in lactation
Use in Lactation: Safe during breastfeeding; human studies show insignificant transfer to breast milk.
Pediatric use
Not for use in children under 2 years.
Geriatric use
Caution required in elderly patients; consult your doctor.
Renal / hepatic impairment
Renal Impairment: Caution when regular applications to broken skin are made to patients with pre-existing renal insufficiency; consult your doctor.
Hepatic Impairment: Caution in liver disease; consult your doctor.
Overdose effects
No overdose information available; consult your doctor if overused.
Storage conditions
Store in a cool and dry place, protected from light; keep out of reach of children.
Chemical structure
Povidone Iodine 5% Topical