Generic
Povidone Iodine 1% Mouth-Wash/Gargle
11 brands available in the market
At a glance
Povidone Iodine 1% Mouth-Wash/Gargle is an antiseptic and disinfectant used to kill germs that cause sore throat. It also relieves dryness or irritation of the mouth and throat and helps prevent and treat oral infections.
Description
Povidone-iodine is an iodophore with powerful broad-spectrum germicidal activity against a wide range of bacteria, viruses, fungi, protozoa, and spores. It oxidizes cell constituents and iodinates proteins, inactivating them. As a mouthwash, it kills harmful microorganisms in the mouth and throat.
Indications
- Sore throat
- Oral infections (gingivitis, mouth ulcers)
- Oral hygiene before, during, and after dental and oral surgery
Therapeutic class
Iodine compounds (Anti-septic Preparations)
Pharmacological class
Antiseptic Mouthwash (Povidone-Iodine)
Pharmacology
Povidone-iodine slowly releases elemental iodine, providing prolonged germicidal activity. It is effective against a wide range of microorganisms including bacteria, viruses, fungi, and spores. As a mouthwash, it oxidizes and inactivates microorganisms on the oral mucosa, preventing infections.
Mechanism of action
Prevents infection by killing harmful microorganisms in the mouth.
Dosage
Adult Dose (Mouthwash/Gargle):
- Use undiluted or diluted with equal volume of warm water
- Gargle or rinse with up to 10 mL for up to 30 seconds without swallowing
- Repeat up to four times daily for up to 14 consecutive days
Pediatric Dose (>6 years):
- Same as adult
Administration
- Check the label before use
- Avoid eating, drinking, or smoking for at least 30 minutes after rinsing
- Do not swallow the solution
Missed dose
If you miss a dose, use it as soon as you remember; skip if it's almost time for next dose; do not double the dose.
Side effects
Side Effects:
- No common side effects seen
Precautions & warnings
- Prolonged use may lead to absorption of significant iodine; do not use for more than 14 days
- Avoid regular use in patients with thyroid disorders or on lithium therapy
- If mouth sores or ulcers do not heal within 14 days, seek medical advice
Contraindications
- Hypersensitivity to povidone iodine or any ingredient
- Prolonged use in thyroid disorders
- Lithium therapy
- Premature neonates or neonates weighing <1.5 kg
Drug interactions
- Concurrent use with lithium therapy may exhibit hypothyroid effect
Food interactions
Not food-related; it is not known whether it is safe to consume alcohol.
Use in pregnancy
Use in Pregnancy: May be unsafe during pregnancy; animal studies have shown harmful effects; consult your doctor.
Use in lactation
Use in Lactation: Safe during breastfeeding; human studies show insignificant transfer to breast milk.
Pediatric use
Not for use in children under 6 years.
Geriatric use
Caution required in elderly patients; consult your doctor.
Renal / hepatic impairment
No interactions found/established for kidney and liver disease.
Overdose effects
No overdose information available; consult your doctor if overused.
Storage conditions
Store in a cool and dry place, protected from light; keep out of reach of children.
Chemical structure
Povidone Iodine 1% Mouth-Wash/Gargle