Ritodrine Hydrochloride

Ritodrine Hydrochloride is vasodilators and uterine relaxants. It is used in the treatment of premature labor (when the uterus starts contracting for birth too early than usual). It works on the muscles of the uterus and helps in relieving the contractions. Ritodrine Hydrochloride can be taken with or without food, but take it at the same time to get the most benefit. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a drink of water. You should take this medicine for as long as it is prescribed for you. The most common side effects of this medicine include chest pain or discomfort, fast or irregular heartbeat, dizziness, drowsiness, dry mouth and loss of appetite. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Before taking the medicine, tell your doctor if you have ever had diabetes, blood pressure, or thyroid. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are breastfeeding or if you experience contraction and water break. Your doctor may perform blood pressure and heart rate check-ups while taking this medicine. It eases the contraction of the uterus and helps relaxing it, thereby preventing premature delivery.

• Premature Labor

A selective beta 2-adrenoceptor agonist with its main action on the uterus, causing relaxation. It reduces the intensity and frequency of contractions. Heart rate is also increased while diastolic pressure is reduced. May cause bronchial relaxation but this is not clinically significant in its usage.

Adult Dose: Oral Uncomplicated premature labour Adult: Start oral therapy 30-60 mins before termination of IV infusion at 10 mg every 2 hr for 24 hr. Subsequently, 10-20 mg every 4-6 hr according to patient's response. Max oral dose 120 mg daily. Parenteral Uncomplicated premature labour Adult: Given as IV infusion, initially 0.05 mg/min. Increase by 0.05 mg/min every 10 min until patient responds. Usual rate: 0.15-0.35 mg/min. As IM inj: 10 mg every 3-8 hr. Maintain for 12-48 hr after the contractions have stopped.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Ritodrine Hydrochloride may be taken with or without food, but it is better to take it at a fixed time.

Common: • Breathlessness • Chest discomfort • Increased glucose level in blood • Increased heart rate • Palpitations • Tremor

[CONSULT YOUR DOCTOR] It is not known whether Ritodrine Hydrochloride alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Ritodrine Hydrochloride is used in the management of premature labour. Avoid over-hydration while taking this medicine. Regularly monitor your blood pressure and pulse rate while on treatment with this medicine. Inform your doctor if you suffer from high blood pressure, diabetes, or thyroid disorders. Inform your doctor immediately if your contractions begin again or your water breaks.

It is contraindicated in patients with known hypersensitivity to the active ingredient or any of the excipients of this component. beta2–agonists are contra-indicated in cardiac disease and in patients with significant risk factors for myocardial ischaemia; they should also be avoided in antepartum haemorrhage, intra-uterine infection, intra-uterine fetal death, placenta praevia, abruptio placenta, threatened miscarriage, cord compression, and eclampsia or severe pre-eclampsia.

May enhance neuromuscular blockade produced by pancuronium and vecuronium. Potentially Fatal: Potassium-depleting drugs may increase risk of hypokalaemia.

[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Ritodrine Hydrochloride. Please consult your doctor.

[SAFE IF PRESCRIBED] Ritodrine Hydrochloride is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

[CONSULT YOUR DOCTOR] Information regarding the use of Ritodrine Hydrochloride during breastfeeding is not available. Please consult your doctor.

[CONSULT YOUR DOCTOR] There is limited information available on the use of Ritodrine Hydrochloride in patients with kidney disease. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Ritodrine Hydrochloride in patients with liver disease. Please consult your doctor.

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