Generic
Sitafloxacin
4 brands available in the market
At a glance
Sitafloxacin — brands, prices, indication, dosage and side effects available in Bangladesh.
Indications
Infections due to susceptible bacteria — respiratory, urinary, skin and some complicated infections.
Pharmacological class
Broad-spectrum fluoroquinolone antibiotic
Mechanism of action
Inhibits bacterial DNA gyrase and topoisomerase IV, stopping DNA replication and killing bacteria.
Dosage
Usually 50–100 mg twice daily depending on the infection (as directed). Complete the full course.
Administration
Take with water; separate from antacids/iron/calcium by at least 2 hours.
Missed dose
Take when remembered; skip if the next dose is near — do not double.
Drug interactions
Antacids/iron/calcium/zinc (reduce absorption), NSAIDs, QT-affecting drugs, warfarin.
Food interactions
Dairy/mineral-rich foods may reduce absorption; separate doses.
Contraindications
Quinolone hypersensitivity; generally avoided in pregnancy and children/adolescents.
Side effects
Stomach upset, diarrhoea, headache; rare: tendon problems, QT prolongation, photosensitivity.
Use in pregnancy
Generally avoided (Category C) — physician's decision if no alternative.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Use in lactation
Generally avoided; seek advice.
Precautions & warnings
Stop if tendon pain occurs; avoid strong sunlight; caution with a seizure history.
Pediatric use
Generally avoided in children/adolescents (joint/tendon risk).
Overdose effects
Vomiting, dizziness; treat supportively.
Therapeutic class
Antibiotic (fluoroquinolone)
Storage conditions
Store below 30°C in a dry place.