Generic
Sucralose
9 brands available in the market
At a glance
Sucralose is a zero-calorie artificial sweetener used as a sugar substitute in tea, coffee, juices, desserts, and various foods. It is suitable for diabetic patients and health-conscious individuals.
Description
Sucralose is an artificial sweetener derived from sucrose where three hydroxyl groups are replaced by three chlorine atoms. It is about 600 times sweeter than sugar. Due to stable carbon-chlorine bonds, it is not metabolized in the body, providing zero calories. It is heat-stable, making it suitable for cooking and baking.
Indications
- Sweetener in tea, coffee, dairy products, juices, desserts, hot and cold beverages
- Sugar substitute for diabetic patients
- Weight management
Therapeutic class
Oral Nutritional Preparations
Pharmacological class
Artificial Sweetener
Pharmacology
Sucralose is a zero-calorie sweetener derived from sucrose. The stable carbon-chlorine bonds prevent it from being metabolized for energy. It does not cross the blood-brain barrier, placental barrier, or mammary gland, so it does not affect fetal or neonatal development. It has no effect on insulin secretion or glucose metabolism.
Mechanism of action
Zero-calorie sweetener as a sugar substitute.
Dosage
Adult Dose (Oral):
- Acceptable daily intake: 5-15 mg/kg body weight
- Normally 1 tablet (8 mg) in a cup of tea or coffee is enough
- Liquid drops: 1 drop = sweetness equivalent to 1 teaspoon of sugar
Administration
- Can be taken with or without food
- Use as directed
Missed dose
If you miss a dose, use it at the next scheduled time.
Side effects
Side Effects:
- No known side effects
Precautions & warnings
- Safe for use during pregnancy and lactation (FDA approved)
Contraindications
No known contraindications
Drug interactions
No known drug interactions
Food interactions
Alcohol is safe with Sucralose.
Use in pregnancy
Use in Pregnancy: Safe during pregnancy; FDA confirmed suitable for everyone; consult your doctor.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Safe during lactation; FDA confirmed suitable for everyone; consult your doctor.
Pediatric use
Safe for children (FDA approved)
Geriatric use
Safe for elderly
Renal / hepatic impairment
Renal Impairment: Safe; consult your doctor.
Hepatic Impairment: Safe; consult your doctor.
Overdose effects
No overdose information available; excessive use may cause mild digestive issues.
Storage conditions
Store below 30°C in a cool and dry place, protected from light; keep out of reach of children.
Chemical structure
Sucralose