Generic
Valganciclovir
1 brands available in the market
At a glance
Valganciclovir is used to treat cytomegalovirus (CMV) infection of the retina (retinitis) in adult patients with acquired immunodeficiency syndrome (AIDS). It is also used for the prevention of CMV infection in patients who have received an organ transplant from a CMV-infected donor.
Description
Valganciclovir is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.
Indications
- Cytomegalovirus (CMV) infection
- CMV retinitis (in AIDS patients)
- Prevention of CMV infection in organ transplant
Therapeutic class
Antiviral
Pharmacological class
Antiviral
Pharmacology
Valganciclovir is an antiviral medication. It prevents the multiplication of virus in human cells.
Mechanism of action
Inhibits viral DNA synthesis, preventing virus multiplication.
Dosage
Adult Dose (Oral):
- Dose and duration will be determined by your doctor
- Dose adjustment may be needed based on renal function
Administration
- Take with food
- Swallow whole; do not chew, crush or break
- Drink plenty of water during treatment
Missed dose
If you miss a dose, take it as soon as possible; if almost time for next dose, skip it; do not double the dose.
Side effects
Common Side Effects:
- Stomach pain
- Decreased red blood cell count
- Diarrhea
- Fever
- Vomiting
- Low white blood cell count
Precautions & warnings
- May decrease alertness; do not drive
- Drink plenty of water during treatment; helps prevent dehydration and kidney damage
- Finish the full course even if you feel better
- Consult doctor if pregnant or breastfeeding
Contraindications
- Hypersensitivity to valganciclovir
Drug interactions
- No known significant interactions
Food interactions
It is not known whether it is safe to consume alcohol with Valganciclovir; consult your doctor.
Use in pregnancy
Use in Pregnancy: May be unsafe; animal studies show harmful effects; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Probably unsafe; may pass into breast milk and harm the baby; consult your doctor.
Pediatric use
Safety and efficacy not established in children
Geriatric use
Caution required in elderly; renal function may be reduced
Renal / hepatic impairment
Renal Impairment: Caution needed; dose adjustment may be needed
Hepatic Impairment: Probably safe; no dose adjustment needed
Overdose effects
Symptoms: Bone marrow suppression, infections.
Treatment: Supportive care.
Storage conditions
Store in a cool and dry place; keep out of reach of children.