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At a glance

Dextrose 100% is an intravenous glucose solution used for short-term fluid replacement, hypoglycemia, and dehydration.

Indications
  • Carbohydrate and fluid depletion
  • Hypoglycemia
  • Dehydration
  • Nutritional support
  • Emergency management of hyperkalemia
Pharmacology

Dextrose is a form of glucose (sugar). Dextrose injection is given intravenously to replace lost fluids and provide carbohydrates to the body. It is used to treat low blood sugar (hypoglycemia), insulin shock, or dehydration (fluid loss).

Dosage

Dosage depends on the clinical condition of the patient. 5% dextrose: 500-1000 ml. 10% solution: 20-30 ml/kg. 25% solution: 10-35 drops/min for adults.
Oral powder: Adults and children (>2 years): 10-20 gm as single dose (may repeat in 10 min if needed).

Side effects

Common: Injection site reactions (pain, swelling, redness), fever, ongoing cough, headache, weakness.
Serious: Breathing difficulty, hallucinations, seizures, arrhythmia, hypokalemia.

Use in pregnancy

Pregnancy Category C. Dextrose 100% may be unsafe during pregnancy. Consult your doctor.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings

Monitor serum glucose concentration; insulin may be needed in diabetic patients. Do not mix with whole blood (hemolysis and clumping may occur). Do not use if solution is cloudy, contains particles, or expired. Avoid in kidney disease, caution in liver disease.

Overdose effects

Overdose may cause hyperglycemia, electrolyte imbalance, respiratory distress, cardiac arrhythmia. Seek medical attention.

Storage conditions

Keep below 30°C temperature, away from light & moisture. Keep out of reach of children.

Dextrose 100% — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.