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At a glance

Diosmin + Hesperidin is a flavonoid combination used for the treatment of varicose veins, chronic venous insufficiency, and hemorrhoids.

Indications
  • Acute hemorrhoidal attacks
  • Chronic hemorrhoidal disease
  • Chronic venous insufficiency (heavy legs, pain, nocturnal cramps)
  • Varicose veins
Pharmacology

Diosmin and Hesperidin is a phlebotonic drug and a vascular protecting agent. It reinforces venous tone by prolonging the activity of parietal noradrenaline. It protects the microcirculation by decreasing leukocyte activation and inhibiting the release of inflammatory mediators, and normalizes capillary permeability.

Dosage

Acute hemorrhoids: First 4 days: 3 tablets daily (450/50 mg) OR 1 tablet TDS (900/100 mg); next 3 days: 2 tablets daily; then maintenance: 1 tablet daily.
Chronic hemorrhoids/Venous insufficiency: 1 tablet twice daily (450/50) OR 1 tablet daily (900/100) for 2-6 months.

Side effects

Common: Diarrhea, dizziness, hives, itching, nausea, erythema, stomach pain, gastric disorders, neurovegetative disorders (feeling of discomfort).

Use in pregnancy

Generally considered safe during pregnancy (no teratogenic effects in animal studies).

Pregnancy Category: N/A — always consult a doctor before taking during pregnancy.

Precautions & warnings

Does not usually affect driving ability (caution if dizziness occurs). If hemorrhoidal symptoms do not disappear within 15 days, consult a doctor. Caution in patients with a history of cancer (no specific studies).

Overdose effects

No adequate information on overdose is available.

Storage conditions

Keep below 30°C temperature, away from light & moisture.

Diosmin + Hesperidin — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.