৳ 1,318/unit
Pack: ৳ 1,318
৳ 1,318/unit
Pack: ৳ 1,318
At a glance
Iopamidol is a contrast agent used to enhance visibility of blood vessels and non-bony structures before an X-ray test or CT scan.
Indications
- Neuroradiology (lumbar myelography, thoraco-cervical myelography)
- Angiography (cerebral angiography, selective coronary angiography, left ventriculography, aortography, angiocardiography)
- Urography
- CT scanning contrast enhancement
- Arthrography
- Fistulography
Pharmacology
Iopamidol is an organic iodine compound used as a non-ionic water soluble radiographic contrast medium. It blocks X-rays as they pass through the body, thereby allowing body structures not containing iodine to be visualized. The degree of opacity produced by Iopamidol is directly proportional to the total amount of the iodinated contrast agent in the path of the X-rays.
Dosage
Adult Dose:
- Neuroradiology (Lumbar/Thoraco-cervical myelography): Iopamidol 370, 6-13 mL
- Cerebral Angiography: Iopamidol 300, 8-12 mL; Iopamidol 370, 6-13 mL
- Selective Coronary Arteriography: Iopamidol 370, 4-8 mL/artery
- Left Ventriculography: Iopamidol 370, 25-50 mL
- Urography: Iopamidol 300, 50 mL IV OR Iopamidol 370, 40 mL IV
- CT Scanning (Head/Body): Iopamidol 300, 100-200 mL IV
Child Dose:
- Angiocardiography (370 mg/mL): <2 years: 10-15 mL IV; 2-9 years: 15-30 mL IV; 10-18 years: 20-50 mL IV
- CT Scanning/Urography: 1-3 mL/kg IV; not to exceed 30 g iodine
Side effects
Side Effects:
- Injection site reactions (pain, swelling, redness)
- Nausea
- Hot flashes
- Arrhythmias, arterial spasm, flushing, vasodilatation
- Dizziness, confusion, paresthesia, visual disturbances, seizure, paralysis, coma
- Coughing, sneezing, rhinitis, asthma, apnea, laryngeal edema
- Muscle spasm
- Severe anaphylactoid reactions (Potentially Fatal)
Use in pregnancy
Use in Pregnancy: Iopamidol injection should be administered only if procedure is considered essential by physician; teratogenicity studies in rats and rabbits showed no influence.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
Precautions:
- Iopamidol does not usually affect your ability to drive
- In myelography, keep patient hydrated and bed head raised
- Patients taking Metformin should stop 48 hours before and after X-ray examination
- Caution in severe liver and kidney disease
- Biguanide oral anti-diabetic agents (Metformin) compete with contrast media for excretion in kidneys
Overdose effects
Overdose: Treatment is directed toward support of all vital functions and prompt institution of symptomatic therapy.
Storage conditions
Store away from light below 30°C; if crystallization occurs, do not use; use immediately after opening; discard any residue.