Amitor 5/105mg+10mg

• Hypertension
• Chronic stable angina
• Coronary Artery Disease (CAD)
• Primary hypercholesterolemia (heterozygous familial and non-familial)
• Mixed dyslipidemia (Fredrickson Types IIa and IIb)
• Hypertriglyceridemia (Fredrickson Type IV)
• Primary dysbetalipoproteinemia (Fredrickson Type III)
• Homozygous Familial Hypercholesterolemia (HoFH)

Amlodipine:

• Hypertension: 5 mg once daily (maximum 10 mg)
• Elderly/Hepatic impairment: Start with 2.5 mg once daily
• Chronic stable/vasospastic angina: 5-10 mg daily

Atorvastatin:

• Hypercholesterolemia & mixed dyslipidemia: Start with 10 mg daily (range 10-80 mg)
• Homozygous FH: 10-80 mg daily
• Renal impairment: No dose adjustment needed
• Hepatic dysfunction: Exposure is increased in moderate-severe disease

• Headache
• Nausea
• Stomach pain
• Flushing
• Ankle swelling
• Palpitations
• Constipation
• Muscle pain
• Tiredness
• Sleepiness
• Increased blood glucose
• Increased liver enzymes

Serious Precautions:

• Patients with severe obstructive coronary artery disease may develop increased frequency of angina or MI when starting calcium channel blocker therapy or increasing dose
• Report any muscle pain, tenderness, or weakness to your doctor
• Report signs of liver damage (abdominal pain, dark urine, yellow skin/eyes)
• Do not use during pregnancy and breastfeeding
• Contraindicated in active liver disease or unexplained liver enzyme elevations (>3x ULN)
• Use with caution in patients with heart failure
• Caution in severe aortic stenosis