৳ 1/unit
Pack: ৳ 1
৳ 1/unit
Pack: ৳ 1
At a glance
Antihemophilic Factor [Factor VIII] is a coagulation factor used to treat and prevent bleeding episodes in hemophilia A.
Indications
Treatment and prophylaxis of hemorrhagic episodes in patients with hemophilia A, and prophylaxis in severe hemophilia A.
Pharmacology
Required for clot formation and maintenance of hemostasis by activating factor X in conjunction with activated factor IX.
Dosage
Mild-moderate hemorrhage: 10-15 IU/kg. Serious/minor surgery: 15-25 IU/kg initially then 10-15 IU/kg q8-12h. Severe hemorrhage/major surgery: 40-50 IU/kg initially then 20-25 IU/kg q8-12h. Prophylaxis: 10-50 IU/kg every 2-3 days.
Side effects
Chills, chest tightness, fever, headache, nausea, vomiting, urticaria, stinging at infusion site, vasomotor reactions with rapid infusion.
Use in pregnancy
Pregnancy Category C. Use if potential benefit justifies potential risk to the fetus.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Risk of intravascular hemolysis in blood groups A, B, or AB receiving high/repeated doses. Risk of viral transmission. Monitor platelet counts.
Overdose effects
Management according to clinical symptoms under medical supervision.
Storage conditions
Store between 2-8°C. Use within 3 hours of reconstitution; do not refrigerate after reconstitution.