৳ 220/unit
Pack: ৳ 220
৳ 220/unit
Pack: ৳ 220
At a glance
Atracurium Besilate is a non-depolarizing neuromuscular blocking agent used to facilitate endotracheal intubation, mechanical ventilation, and muscle relaxation during surgery.
Indications
Indicated for endotracheal intubation, facilitating mechanical ventilation in intensive care, and as a muscle relaxant in general anaesthesia.
Pharmacology
Antagonizes acetylcholine at the motor end-plate cholinergic receptors. Neuromuscular blockade can be reversed by acetylcholinesterase inhibitors like neostigmine.
Dosage
Adult and Child (>1 month): Initially 300-600 mcg/kg as IV bolus, with maintenance doses of 100-200 mcg/kg IV every 15-25 min or 5-10 mcg/kg/min by infusion.
Side effects
Flush, erythema, pruritus, urticaria, wheezing, bronchospasm, bradycardia, injection site reactions. Potentially fatal: Anaphylaxis.
Use in pregnancy
Pregnancy Category C. Use only if potential benefit justifies potential risk.
Pregnancy Category: Category C — always consult a doctor before taking during pregnancy.
Precautions & warnings
Use with caution in patients with cardiovascular disease, asthma, burn injuries, myasthenia gravis, or electrolyte imbalances.
Overdose effects
Causes histamine release and hypotension; requires artificial ventilation and cardiovascular support.
Storage conditions
Store between 2-8°C. Do not freeze. Protect from light.