৳ 54.84/unit
Pack: ৳ 1,700.04
৳ 54.84/unit
Pack: ৳ 1,700.04
At a glance
Ibandronic Acid + Calcium + Vitamin D3 kit is used for the treatment and prevention of osteoporosis, increasing Bone Mineral Density (BMD) and reducing the incidence of vertebral fractures.
Indications
- Treatment and prevention of osteoporosis
- Increases Bone Mineral Density (BMD)
- Reduces incidence of vertebral fractures
Pharmacology
Ibandronic Acid is a nitrogen-containing bisphosphonate that inhibits osteoclast-mediated bone resorption. Coral Calcium is composed of Calcium Carbonate with small amounts of Magnesium and other Trace minerals, ensuring better absorption due to its chemical similarity to human bone Calcium Carbonate. Vitamin D3 aids in calcium absorption from the GI tract and helps maintain calcium balance in the body.
Dosage
Dosing Schedule (Oral):
- Day 1: Take one Ibandronic Acid tablet on empty stomach (1 hour before breakfast with plain water); do not lie down for 60 minutes; do not chew or suck the tablet
- Day 2-31: Take one Calcium & Vitamin D3 tablet morning and evening after meal
Adult Dose: Ibandronic Acid 150 mg once monthly on same date each month; Calcium 500 mg & Vitamin D3 200 IU (2 tablets daily in divided doses)
Child Dose: Safety and efficacy in pediatric patients have not been established
Side effects
Ibandronic Acid: Hypertension, Dyspepsia, Nausea, Diarrhea, Abdominal Pain, Arthralgia, Back Pain, Myalgia, Muscle Cramp, Influenza, Nasopharyngitis, Bronchitis, Urinary Tract Infection, Upper Respiratory Tract Infection, Headache, Dizziness, Skin rash, Insomnia
Calcium & Vitamin D3: Flatulence, diarrhea, constipation, upper GI discomfort; hypercalciuria and hypercalcemia (rare with prolonged use)
Use in pregnancy
Use in Pregnancy: Category C; no adequate and well-controlled studies in pregnant women; use only if potential benefit justifies potential risk to mother and fetus.
Precautions & warnings
Precautions:
- Ibandronic Acid: Caution in active upper GI problems (Barrett's esophagus, dysphagia, gastritis, duodenitis, ulcers)
- Treat hypocalcemia and other bone/mineral disturbances before starting therapy
- Severe bone, joint and muscle pain reported
- Osteonecrosis of the jaw reported
- Calcium & Vitamin D3: Reduce dose in mild hypercalciuria; monitor plasma and serum calcium in mild to moderate renal impairment; increase fluid intake if history of kidney stones
Overdose effects
Overdose: Oral overdose of Ibandronic acid may result in hypocalcemia, hypophosphatemia and upper gastrointestinal adverse events; milk or antacids should be given.
Storage conditions
Do not store above 30°C; keep away from light and out of reach of children.