৳ 3.72/unit
Pack: ৳ 3.72
৳ 3.72/unit
Pack: ৳ 3.72
At a glance
Tulobuterol Hydrochloride is used for the treatment of asthma and chronic obstructive pulmonary disorder (COPD). It helps in relaxing the muscles of the air passages, thus widening it and making it easier to breathe.
Indications
- Asthma
- Chronic obstructive pulmonary disease (COPD)
- Bronchial asthma
- Chronic bronchitis
- Asthmatic bronchitis
- Pulmonary emphysema
- Bronchiectasis
Pharmacology
Tulobuterol is a direct-acting sympathomimetic with selective action on β2-receptors. The primary pharmacological action of beta-adrenergic drugs is to stimulate adenyl cyclase, the enzyme which catalyzes the formation of cyclic AMP from ATP. The cyclic AMP thus formed mediates the cellular response that results in bronchodilation.
Dosage
Adult Dose (Oral):
- Bronchodilation: Initially 1-2 mg twice daily; increase to 2 mg three times daily if necessary
- Tablets: Start 1 mg twice daily; may increase to 2 mg twice daily after 7-10 days; may increase to 6 mg/day if necessary
Child Dose (Oral):
- 1-6 years: 0.25-0.5 mg twice daily
- 6-10 years: 0.5-1 mg twice daily
- 10-14 years: 1-1.5 mg twice daily
- Syrup: 40-80 mcg/kg/day in two divided doses
Side effects
Common Side Effects:
- Tremor
- Headache
- Restlessness
- Insomnia
- Palpitations
- Muscle cramp
- Hypertension
- Angina
- Tachycardia
- Vomiting
- Vertigo
- CNS stimulation
Use in pregnancy
Use in Pregnancy: Information not available; consult your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Unknown if alters ability to drive; caution advised
- Use long-term only in patients whose asthma cannot be adequately controlled on controller medications alone
- Use with caution in diabetes mellitus, hypertension, hyperthyroidism, and seizure disorders
- Caution in renal failure; kidney is principal route of elimination
- Dosage may require individualization in impaired liver function
- Administer cautiously to cardiac patients, especially those with arrhythmias, coronary insufficiency, or myocardial ischemia
Overdose effects
Symptoms: Tremor, tachycardia, palpitations, hypotension.
Treatment: Supportive care.
Storage conditions
Store in a dry place, away from light and moisture; keep out of reach of children.