৳ 15/unit
Pack: ৳ 15
৳ 15/unit
Pack: ৳ 15
At a glance
Celiprolol Hydrochloride belongs to a group of medicines called beta-blockers. It is used for treating hypertension (high blood pressure) and angina (heart-related chest pain).
Indications
- Hypertension (high blood pressure)
- Angina (heart-related chest pain)
Pharmacology
Celiprolol is a vasoactive beta-1 selective adrenoceptor antagonist with partial beta-2 agonist activity. The beta-2 agonist activity is thought to account for its mild vasodilating properties. It lowers blood pressure in hypertensive patients at rest and on exercise. The effects on heart rate and cardiac output are dependent on the pre-existing background level of sympathetic tone. Under conditions of stress such as exercise, celiprolol attenuates chronotropic and inotropic responses to sympathetic stimulation. However, at rest minimal impairment of cardiac function is seen.
Dosage
Adult Dose (Oral):
| Condition | Initial Dose | Maintenance Dose | Maximum Dose |
|---|---|---|---|
| Hypertension | 200 mg | 200-400 mg | 400 mg/day |
(After 2-4 weeks, your doctor may increase the dose to 400 mg once daily if needed)
Renal Dose: CrCl 15-40 ml/min: 100-200 mg/day; CrCl <15 ml/min: Avoid use.
Hepatic Dose: Low doses are recommended in patients with liver problems.
Side effects
Common Side Effects (may affect up to 1 in 10 people):
- Dizziness or light headedness
- Weakness
- Fainting especially when standing up from a lying position
- Skin rashes
- Excessive itching
- Nausea
- Headache
- Fatigue
- Constipation
- Diarrhea
Serious Side Effects: Allergic reaction (rash, swallowing or breathing problems, swelling of face/lips/throat/tongue), flu-like symptoms, swollen or painful joints, increased sensitivity to sunlight, hair loss, abdominal pain, anaemia (may indicate Systemic Lupus Erythematosus).
Use in pregnancy
[CONSULT YOUR DOCTOR] Celiprolol Hydrochloride is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor. Pregnancy Category C. Close monitoring of the neonate is recommended for the first 3 to 5 days of life if taken during pregnancy.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- [UNSAFE] Celiprolol Hydrochloride may cause side effects which could affect your ability to drive. You may feel dizzy or tired, have problems seeing, shaking or headaches whilst taking it.
- It may cause dizziness. If this happens, get up slowly when rising from a sitting or lying position.
- It can hide symptoms of low blood sugar if you are diabetic. Monitor your blood sugar levels regularly.
- Do not stop taking Celiprolol Hydrochloride suddenly as it can cause your blood pressure to rise suddenly, thereby increasing the risk of heart attack and stroke.
- Consult your doctor if you have liver or kidney problems, Prinzmetal's angina, Raynaud's disease, psoriasis, asthma, thyroid problems, diabetes, or controlled heart failure.
Overdose effects
Overdose symptoms may include: slow heart beats, low blood pressure, feeling dizzy or weak, difficulty in breathing, wheezing or heart problems. Contact your doctor or go to the nearest hospital casualty department immediately.
Storage conditions
Keep container in the outer carton. Do not store above 25°C. Do not use this medicine after the expiry date which is stated on the carton.