৳ 1,000/unit
Pack: ৳ 1,000
৳ 1,000/unit
Pack: ৳ 1,000
At a glance
Oral Cholera Vaccine is used for active immunization against Vibrio cholerae. It is administered to individuals above 1 year of age and is effective in preventing cholera infection.
Indications
- Active immunization against Vibrio cholerae
- Prevention of cholera in individuals 1 year and above
Pharmacology
Oral Cholera Vaccine contains V. cholerae O1 (Inaba and Ogawa) and O139 strains inactivated by heat and formaldehyde. After oral administration, it induces local immunity in the intestinal mucosa providing protection against Vibrio cholerae.
Dosage
Adults and Children (>1 year):
- Primary vaccination: 1.5 ml (1 dose) orally, 2 doses at 2-week intervals
- Onset of protection: 7-10 days after completion of primary series
Side effects
Side Effects:
- Acute gastroenteritis
- Diarrhea
- Fever
- Vomiting
- Abdominal pain
- Itching
- Rash
- Nausea
- Weakness
- Cough
- Vertigo
- Dry mouth
- Oral ulcer (rare)
- Sore throat (rare)
- Yellowing of urine (rare)
Incidence of adverse events less after second dose compared to first.
Use in pregnancy
Use in Pregnancy: No specific clinical studies performed; may be considered after careful evaluation of benefits and risks in emergency or epidemic.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Vaccination should be delayed in acute febrile illness or acute GI illness
- Not recommended for children <2 years
- Immunocompromised patients may not obtain expected immune response
- Vaccine does not provide 100% protection; additional preventive measures
- Medical observation for at least 30 minutes after vaccination
Overdose effects
No information on overdose; symptomatic treatment.
Storage conditions
Store at +2°C to +8°C; transport also at +2°C to +8°C; do not freeze; discard if frozen; protect from light.